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临床试验/NCT01083927
NCT01083927已完成不适用

Rotational Narrow Strip Versus Full Conjunctival Graft in Pterygium Excision

University of Malaya2 个研究点 分布在 1 个国家目标入组 94 人开始时间: 2007年7月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
94
试验地点
2
主要终点
Recurrence Rate of Pterygium operated with Rotational Narrow Strip Conjunctival Graft and Full Conjunctival Graft Excision

研究概览

简要总结

To compare the efficacy of rotational narrow strip conjunctival graft to full conjunctival graft in primary pterygium excision. Risk analysis of factors that may affects the recurrence rate.

详细描述

Pterygium is a raised, wing-shaped growth of fibrovascular tissue that extends horizontally from the bulbar conjunctiva, crossing the limbus, and onto the cornea. It is a common ocular surface disease in Malaysia.

Pterygium can cause chronic ocular irritation, redness, tearing, visual impairment and poor cosmesis. Treatment of symptomatic pterygium remains surgical. Surgery should achieve low recurrence rate and acceptable cosmesis. Various surgical techniques had been described with variable success.

In this study, we compared the efficacy of Rotational Narrow Strip Conjunctival Graft with the conventional full conjunctival graft in pterygium excision. Patient will be follow up for a year after pterygium surgery. Outcome will be recurrence rate between the two groups at one year. Risk analysis of certain factors that affects the recurrence rate will be discussed.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
21 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Significant and symptomatic primary pterygium clinically requiring excision
  • Willingness to participate in research project and to attend research time

排除标准

  • Age < 21 years
  • Glaucoma in the study eye
  • Other concurrent ocular surface pathology
  • Infection of the ocular surface
  • Poor general health

结局指标

主要结局

Recurrence Rate of Pterygium operated with Rotational Narrow Strip Conjunctival Graft and Full Conjunctival Graft Excision

时间窗: 1 year

次要结局

  • Analysis of risk factors associated with recurrence of pterygium(1 year)

研究者

申办方类型
Other

研究点 (2)

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