NCT06277206
Completed
Not Applicable
A Study Using 18F-FAPI PET to Evaluate Pathologic Response to Systemic Treatment in Pancreatic Adenocarcinoma
Zhejiang University1 site in 1 country59 target enrollmentAugust 4, 2021
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- 18F-FAPI
- Sponsor
- Zhejiang University
- Enrollment
- 59
- Locations
- 1
- Primary Endpoint
- Change of Mean standardized uptake value
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
To explore the potential utility of 18F-FAPI-04 PET/CT for pathologic response evaluation to systemic treatment in PDAC
Investigators
TingBo Liang
Professor
Zhejiang University
Eligibility Criteria
Inclusion Criteria
- •suspected to have pancreatic cancer by radiological imaging
- •planned systemic treatment
- •possibility of conversion surgery
- •willingness to participate the study
Exclusion Criteria
- •without pathologically confirmed pancreatic cancer
- •poor performance status or organ functions that cannot meet the systemic treatment requirements
- •metastatic disease
- •pregnant patients
Outcomes
Primary Outcomes
Change of Mean standardized uptake value
Time Frame: Baseline and preoperation
Change of SUVmean before and after treatment
Change of Maximum standardized uptake value
Time Frame: Baseline and preoperation
Change of SUVmax before and after treatment
Secondary Outcomes
- Mean standardized uptake value(Baseline)
- Change of Total Lesion FAP expression(Baseline and preoperation)
- Maximum standardized uptake value(Baseline)
- Metabolic Tumor Volume(Baseline)
- Change of Metabolic Tumor Volume(Baseline and preoperation)
- Total Lesion FAP expression(Baseline)
Study Sites (1)
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