Longitudinal Pattern of Streptococcus Pneumoniae Nasopharyngeal Carriage and Antimicrobial Susceptibility in Healthy Children Aged Less Then 5 Years, in the Area of Milan and Surroundings, Lombardy, Italy.

University of Milan1 site in 1 country1,300 target enrollmentSeptember 2011

ConditionsStreptococcus Pneumoniae Nasopharyngeal Carriage

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Streptococcus Pneumoniae Nasopharyngeal Carriage
Sponsor: University of Milan
Enrollment: 1300
Locations: 1
Primary Endpoint: • circulation of antimicrobial non-susceptible Streptococcus pneumoniae strains in healthy children aged less than 5 years
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The objective of this active surveillance study is to make available crucial data about epidemiology, serotype distribution, and longitudinal pattern of antibiotic susceptibility of nasopharyngeal strains of Streptococcus pneumoniae carried in the population of healthy children aged less than years and living in the area of Milan and surroundings, Lombardy, Italy.

To estimate the nasopharyngeal carriage rate and longitudinal pattern of Streptococcus pneumoniae in healthy children aged less than 5 years living in the area of Milan, Italy;
To describe the circulation of antimicrobial non-susceptible Streptococcus pneumoniae strains in healthy children aged less than 5 years

Secondary objectives:

To describe the nasopharyngeal carriage distribution of Streptococcus pneumoniae strains in healthy subjects less than 5 years old;
To examine the role of risk factors in the Streptococcus pneumoniae carriage rate in healthy children;
• To evaluate the possible impact of vaccination policy in the referenced population.

Registry

clinicaltrials.gov

Start Date

September 2011

End Date

TBD

Last Updated

14 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University of Milan

Responsible Party

Principal Investigator

Gian Vincenzo Zuccotti

professor of Pediatrics

University of Milan

Eligibility Criteria

Inclusion Criteria

•To estimate the nasopharyngeal carriage rate and longitudinal pattern of Streptococcus pneumoniae in healthy children aged less than 5 years living in the area of Milan, Italy;
•To describe the circulation of antimicrobial non-susceptible Streptococcus pneumoniae strains in healthy children aged less than5 years

Exclusion Criteria

•To describe the nasopharyngeal carriage distribution of Streptococcus pneumoniae strains in healthy subjects less than 5 years old;
•To examine the role of risk factors in the Streptococcus pneumoniae carriage rate in healthy children;
•To evaluate the possible impact of vaccination policy in the referenced population..

Outcomes

Primary Outcomes

• circulation of antimicrobial non-susceptible Streptococcus pneumoniae strains in healthy children aged less than 5 years

Time Frame: 1 year

Secondary Outcomes

• the nasopharyngeal carriage distribution of Streptococcus pneumoniae strains in healthy subjects less than 5 years old;(1 year)
• the role of risk factors in the Streptococcus pneumoniae carriage rate in healthy children;(1 year)
• the possible impact of vaccination policy in the referenced population(1 year)