Randomized Comparative Trial of Flunarizine Vs Magnesium in the Prophylaxis of Migraine attacks.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 70
- 试验地点
- 1
研究概览
简要总结
Migraine is a neurological disorders characterized by recurrent episodes of severe, unilateral headaches often accompanied by nausea, vomiting, photophobia and phonophobia. In India prevalence of migraine is approximately 25 percent which is greater than the global average. Flunarizine is a calcium channel blocker ,has been extensively studied and proven effective for preventing migraine. Recent studies have also shown promising results for magnesium in migraine prophylaxis. This study seeks to bridge the knowledge gap in migraine prophylaxis by directly comparing the efficacy, safety, and tolerability of flunarizine and magnesium in Indian population, where limited region specific-evidence currently exists, thereby informing clinical decision making and optimizing treatment outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients diagnosed with migraine without aura according to the diagnostic criteria specified by ICHD-3 (International classification of headache disorders) Patients having no abnormal findings on systemic and neurological examination.
- •Having more than 3 migraine attacks per month.
- •Not having taken any prophylactic medicines for migraine in the last 4 months Patients who provide consent.
排除标准
- •Suffering from heart, liver, and renal diseases.
- •A blood pressure over 180/95 mm of Hg, pregnancy or lactation.
- •Usage of alcohol and drug abuse.
- •Patients not willing to participate in the study.
研究者
DrSmitha Chandra B C
PESU Institute of medical sciences and research