Efficacy of Oral Sucrose and Topical Anesthetics to Reduce Pain During Eye Examination for Retinopathy of Prematurity
- Conditions
- Investigate the Efficacy of Sucrose During Eye Examination
- Registration Number
- NCT01811979
- Lead Sponsor
- Dr. Sami Ulus Children's Hospital
- Brief Summary
Oral sucrose reduces pain during heel sticks and venipunctures in preterm infants. The purpose of this study was to determine the effectiveness of local anesthetic eye drops and a pacifier, plus repeated doses of 24% sucrose, to relieve pain associated with eye examinations for retinopathy of prematurity.
- Detailed Description
Oral sucrose reduces pain during heel sticks and venipunctures in preterm infants. Administration of oral sucrose with and without non-nutritive sucking is the most frequently studied non-pharmacological intervention for procedural pain relief in neonates.The purpose of this study was to determine the effectiveness of local anesthetic eye drops and a pacifier, plus repeated doses of 24% sucrose, to relieve pain associated with eye examinations for retinopathy of prematurity.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
-VLBW infants <32 weeks of gestational age
- infants >32 weeks of gestational age
- neuromuscular abnormality
- major abnormality
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Premature Infant Pain Profile two hours Premature Infant Pain Profile were determined after each eye examination
- Secondary Outcome Measures
Name Time Method Crying time two hours Crying time will be determined after each eye examination
Trial Locations
- Locations (1)
Dr Sami Ulus Children Hospital
🇹🇷Ankara, Turkey
Dr Sami Ulus Children Hospital🇹🇷Ankara, Turkey