Efficacy of Oral Sucrose and Topical Anesthetics to Reduce Pain During Eye Examination
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Premature Infant Pain Profile
研究概览
简要总结
Oral sucrose reduces pain during heel sticks and venipunctures in preterm infants. The purpose of this study was to determine the effectiveness of local anesthetic eye drops and a pacifier, plus repeated doses of 24% sucrose, to relieve pain associated with eye examinations for retinopathy of prematurity.
详细描述
Oral sucrose reduces pain during heel sticks and venipunctures in preterm infants. Administration of oral sucrose with and without non-nutritive sucking is the most frequently studied non-pharmacological intervention for procedural pain relief in neonates.The purpose of this study was to determine the effectiveness of local anesthetic eye drops and a pacifier, plus repeated doses of 24% sucrose, to relieve pain associated with eye examinations for retinopathy of prematurity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 1 Day 至 3 Months（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •VLBW infants <32 weeks of gestational age
排除标准
- •infants >32 weeks of gestational age
- •neuromuscular abnormality
- •major abnormality
结局指标
主要结局
Premature Infant Pain Profile
时间窗: two hours
Premature Infant Pain Profile were determined after each eye examination
次要结局
- Crying time(two hours)
研究者
Dilek Dilli
Assoc Prof
Dr. Sami Ulus Children's Hospital