Pain control effectiveness of curcumin compare with ibuprofen after lower third molar removal surgery and A double blind randomized clinical trial

Ministry of Higher Education, Science, Research and Innovation, Prince of Sonkla University0 个研究点目标入组 76 人开始时间: 2022年7月5日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. Patients aged between 18 to 29 years
•2. Weight 40-90 kgs
•3. Clear indication for removal of lower third molars
•3. Health patients with no uncontrolled systemic disease that is unsuitable to lower the third molar impacted
•4. The moderate difficulty of lower third molar (Pederson difficulty index 5-6 score)
•5. Operation time must be less or equal to 1 hour
•6. An absence of periodontal disease, infection, swelling before surgery
•7. Same person to surgery second time greater than or equal to 3 weeks

•1. Taking analgesic medications, such as aspirin, paracetamol, NSAIDs, opioids, or any other agents between 24 hours and 2 weeks before surgery
•2. Patients with a history of severe asthma, gastrointestinal disorders such as Dyspepsia or Peptic ulcer(PU)) Bile duct obstruction, hematologic, renal, or hepatic disease; immunosuppressive disorder; neurological disorder affecting pain perception
•3. Taking medication (use anticoagulant or antiplatelet, cancer drugs)
•4. Pregnancy and Lactation
•Allergy to Local anesthetic, NSAID(Ibuprofen), curcumin, amoxicillin, tramadol, and paracetamol
•5. Smoking

发起方

Ministry of Higher Education, Science, Research and Innovation, Prince of Sonkla University