Combined effect of cognition and coordination exercises(Cognitive Coordination Therapy CCT) on Balance, ability to move around the environment and time taken to react in patients with Parkinsons disease.

Phase 2

Not yet recruiting

Conditions: Parkinsons disease,

Registration Number: CTRI/2025/05/087845

Brief Summary: Falls and balance problems are among the motor impairments that are two to three times more frequent than healthy older adults. Disruptions in Interlimb co-ordination (ILC) have been associated with affections in dynamic stability and functional mobility in persons with PD. Cognitive Rehabilitation Therapy (CRT) is found to be useful to improve cognition, functional disability and quality of life in demented as well as non-demented patients with PD. Reaction time (RT), often used as a measure of cognitive functioning which is often slower in PD can be closely linked to incoordination as both involve the brain’s processing and execution of motor responses. CRT when incorporated into physical performance to improve co-ordination makes up a novel strategy: Cognitive Co-ordination Therapy (CCT). Combining coordination and cognition training for Parkinson’s disease may prove as a promising approach that targets both motor and cognitive functions, addressing the multifaceted nature of the disease. Ergo, this study aims to devise a holistic treatment approach- Cognitive Co-ordination Therapy (CCT) and find out if there are any effects on functional mobility, balance and RT. After obtaining ethical permission, patients meeting the predefined criteria will be recruited. All the participants will undergo mFSST (modified Four Square Step Test), Timed Up and Go test (TUG) and perform Deary Leiwald Reaction Time task pre and post intervention. Computer generated randomization tables will divide them into two groups. Group A will receive Conventional therapy along with CCT while Group B will receive only conventional therapy. Intervention will be for 3 times a week for 4 weeks. Data collected will be analyzed to study the effect of CCT on balance, RT and functional mobility. If the data is normally distributed, then intra and inter group analysis will be done by using paired and unpaired t-test respectively. If the data is not normally distributed, then Mann-Whitney U test and Wilcoxon Signed Rank test will be used for intra and inter group analysis respectively.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 34

Inclusion Criteria

Males and Females diagnosed with idiopathic PD, PD individuals classified under Hoehn Yahr stage 1-3 and Community ambulatory patients.

Exclusion Criteria

Any acute cardiovascular or musculoskeletal condition, Uncontrolled diabetes or hypertension, Uncorrected visual/hearing deficits and Patients not willing to participate.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Balance, Reaction Time, Functional Mobility	Baseline and after 4 weeks of intervention

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): P.T. School and center Seth GSMC Parel Mumbai
🇮🇳
Mumbai, MAHARASHTRA, India
P.T. School and center Seth GSMC Parel Mumbai
🇮🇳Mumbai, MAHARASHTRA, India
Lakshmiprabha R
Principal investigator
9870487879
laps2204@gmail.com