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Comparison of efficacy of a new painkiller medicine namely Lornoxicam (extended release) and commonly used medicine Diclofenac for pain control following impacted wisdom teeth removal

Phase 4
Conditions
Health Condition 1: K011- Impacted teeth
Registration Number
CTRI/2024/02/062947
Lead Sponsor
Terna Dental College
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients who are willing to participate in the study

2.Patients requiring surgical extraction of bilateral impacted mandibular 3rd molar of similar difficulty (easy or moderate difficulty as per Pederson’s difficulty index)

3.Healthy patients belonging to ASA Class I or II will be included

4.Patients who are not on any pain management therapy or those who have not consumed any NSAID in the last seven days.

Exclusion Criteria

1.Patients not willing to participate in the study

2.H/o Hypersensitivity reactions to Lornoxicam, Diclofenac or any other NSAID

3.Pregnant and lactating patients

4.Patients suffering from Bronchial Asthma or COPD or bleeding diathesis.

5.Patients with H/o gastritis, gastric/ duodenal ulcers, or any other inflammatory gastrointestinal disease

6.Pederson difficulty index score 7-10 (Difficult)

7.Patients having local signs of infection around the impacted tooth to be removed such as periapical abscess/granuloma, pericoronal abscess, fascial space infection etc.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain evaluation using modified visual analogue scale (0-10)Timepoint: 4 hour, 8 hour, 12 hour, 24 hour, 48 hour, 72 hour
Secondary Outcome Measures
NameTimeMethod
Swelling evaluation described by Gabka and Matsumara scaleTimepoint: Postoperative Day 1 and Postoperative Day 3
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