The Efficacy of Ultrasound Guided Continuous Quadratus Lumborum Block Versus Continuous Paravertebral Block In Radical Cystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- analgesic effect
研究概览
简要总结
The aim of the study to compare between intraoperative and postoperative analgesic effect of ultrasound guided continuous quadratus lumborum block and continuous thoracic paravertebral block in patients operated for radical cystectomy (primary outcome). Side effects, length of hospital stay and patient satisfaction(secondary outcome).
详细描述
The analgesic efficacy of ultrasound guided continuous quadratus lumborum block versus continuous paravertebral block in radical cystectomy
Protocol of a thesis submitted to the Faculty of Medicine University of Alexandria In partial fulfillment of the requirements of the degree of Master of Anaesthesia And Surgical Intensive Care
By
Amr Ragheb Hieba MBBCh, Alex. Resident Alexandria University Hospitals Department of Anaesthesia and Surgical Intensive Care Faculty of Medicine University of Alexandria 2017
SUPERVISORS
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
盲法说明
The patients, outcome assessors and care providers are not informed with the block type done.
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• After written informed consent from each patient or oral consent if illiteracy prevent a written consent, The present study will be carried out in the Urosurgery department at Alexandria Main University hospital on 60 adult patients scheduled for radical cystectomy, males and females.
- •Patients will be randomly assigned into two equal groups (30 patients each) according to type of the block:
- •Patients will receive ultrasound guided quadratus lumborum block with 0.3 ml /kg bupivacaine 0.25% on each side with catheter insertion for maintenance doses 0.1ml/kg/hr on each side.
- •Patients will receive ultrasound guided thoracic paravertebral block with 0.3 ml/kg bupivacaine 0.25 % on each side with catheter insertion for maintenance doses 0.1 ml/kg/hr on each side.
排除标准
- •Patient refusal.
- •Coagulopathy/ thrombocytopenia.
- •Localized infection at the proposed site of injection.
- •Inability to comprehend the scoring systems to be employed due to mental problems.
- •known allergy to the drugs to be used (local anesthetics, opioids)
- •Opioid tolerance/ dependence
- •Back abnormalities.
- •Neurological deficits.
研究组 & 干预措施
US guided Quadratus Lumborum block
Patients will receive ultrasound guided quadratus lumborum block with 0.3 ml /kg bupivacaine 0.25% on each side with catheter insertion for maintenance doses 0.1ml/kg/hr on each side.
干预措施: US guided Quadratus Lumborum block (Procedure)
US guided Paravertebral block.
Patients will receive ultrasound guided thoracic paravertebral block with 0.3 ml/kg bupivacaine 0.25 % on each side with catheter insertion for maintenance doses 0.1 ml/kg/hr on each side.
干预措施: US guided Paravertebral block. (Procedure)
结局指标
主要结局
analgesic effect
时间窗: 72 hours
Visual Analogue Scale measure and needed postoperative analgesics.0 to 10, as 0 no pain 10 the worst pain.
次要结局
- length of hospital stay(30 days)
- Side effects(30 days)
- Patient satisfaction.(30 days)
研究者
Mohammad Hazem I. Ahmad Sabry
Lecturer of Anesthesia
University of Alexandria