The Efficacy of Ultrasound Guided Continuous Quadratus Lumborum Block Versus Continuous Paravertebral Block In Radical Cystectomy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Alexandria
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- analgesic effect
Study Overview
Brief Summary
The aim of the study to compare between intraoperative and postoperative analgesic effect of ultrasound guided continuous quadratus lumborum block and continuous thoracic paravertebral block in patients operated for radical cystectomy (primary outcome). Side effects, length of hospital stay and patient satisfaction(secondary outcome).
Detailed Description
The analgesic efficacy of ultrasound guided continuous quadratus lumborum block versus continuous paravertebral block in radical cystectomy
Protocol of a thesis submitted to the Faculty of Medicine University of Alexandria In partial fulfillment of the requirements of the degree of Master of Anaesthesia And Surgical Intensive Care
By
Amr Ragheb Hieba MBBCh, Alex. Resident Alexandria University Hospitals Department of Anaesthesia and Surgical Intensive Care Faculty of Medicine University of Alexandria 2017
SUPERVISORS
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Care Provider, Outcomes Assessor)
Masking Description
The patients, outcome assessors and care providers are not informed with the block type done.
Eligibility Criteria
- Ages
- 18 Years to 99 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •• After written informed consent from each patient or oral consent if illiteracy prevent a written consent, The present study will be carried out in the Urosurgery department at Alexandria Main University hospital on 60 adult patients scheduled for radical cystectomy, males and females.
- •Patients will be randomly assigned into two equal groups (30 patients each) according to type of the block:
- •Patients will receive ultrasound guided quadratus lumborum block with 0.3 ml /kg bupivacaine 0.25% on each side with catheter insertion for maintenance doses 0.1ml/kg/hr on each side.
- •Patients will receive ultrasound guided thoracic paravertebral block with 0.3 ml/kg bupivacaine 0.25 % on each side with catheter insertion for maintenance doses 0.1 ml/kg/hr on each side.
Exclusion Criteria
- •Patient refusal.
- •Coagulopathy/ thrombocytopenia.
- •Localized infection at the proposed site of injection.
- •Inability to comprehend the scoring systems to be employed due to mental problems.
- •known allergy to the drugs to be used (local anesthetics, opioids)
- •Opioid tolerance/ dependence
- •Back abnormalities.
- •Neurological deficits.
Arms & Interventions
US guided Quadratus Lumborum block
Patients will receive ultrasound guided quadratus lumborum block with 0.3 ml /kg bupivacaine 0.25% on each side with catheter insertion for maintenance doses 0.1ml/kg/hr on each side.
Intervention: US guided Quadratus Lumborum block (Procedure)
US guided Paravertebral block.
Patients will receive ultrasound guided thoracic paravertebral block with 0.3 ml/kg bupivacaine 0.25 % on each side with catheter insertion for maintenance doses 0.1 ml/kg/hr on each side.
Intervention: US guided Paravertebral block. (Procedure)
Outcomes
Primary Outcomes
analgesic effect
Time Frame: 72 hours
Visual Analogue Scale measure and needed postoperative analgesics.0 to 10, as 0 no pain 10 the worst pain.
Secondary Outcomes
- length of hospital stay(30 days)
- Side effects(30 days)
- Patient satisfaction.(30 days)
Investigators
Mohammad Hazem I. Ahmad Sabry
Lecturer of Anesthesia
University of Alexandria