Home-based exergaming for enhancing resistance to falls after stroke (HEROES): Proof-of-principle evaluation.

Conditions: Cerebro vascular accident (CVA)
Stroke
10042258

Registration Number: NL-OMON56779

Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 60

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all
of the following criteria:
- Age between 18 and 75 years old.
- Have sustained a unilateral stroke in the cerebrum more than 6 months ago.
- Have completed inpatient rehabilitation within the past two years.
- Experiencing mild to moderate impairments in balance and walking.
- Physically able to stand and walk independently (Functional Ambulation
Categories score >=4).
- Living in the community.

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded
from participation in this study:
- Conditions in which physical activity is contra-indicated.
- Conditions in which reactive step training on the GRAIL is contra-indicated.
- Any other neurological or musculoskeletal conditions affecting balance or
gait abilities.
- Impaired vision that is not corrected by glasses or lenses.
- Severe cognitive problems based on the Montreal Cognitive Assessment.
- Persistent visuo-spatial neglect based on the Star-Cancellation Test.
- Use of psychotropic drugs or other medication negatively affecting balance.
- Behavioural problems interfering with compliance to the study protocol.
- Unable to use the intervention system independently.
- Unable to give a personal informed consent.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome is the quality of the reactive stepping response following<br /><br>perturbations from standstill. The quality will be expressed as the angle of<br /><br>the stepping leg relative to the vertical at foot contact. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Multiple stepping threshold in the forward and backward direction.<br /><br>- Spatiotemporal step characteristic (step onset, step duration, step length<br /><br>and step velocity) and anticipatory step characteristics (forward lean and<br /><br>weight-bearing assymetry) at the multiple stepping threshold in the forward and<br /><br>backward direction, as these parameters have the potential to explain the<br /><br>presence or absence of differences in the primary outcome.<br /><br>- Clinical outcome measures (Fugl-Meyer Motor Assessment lower extremity<br /><br>subscale, Trunk Impairment Scale, Mini-BESTest, Functional Ambulation Category,<br /><br>10-meter Walk Test, Dynamic Gait Index). This standardized core set of post<br /><br>stroke balance and mobility assessments will be performed according to the<br /><br>consensus-based recommendations from the Stroke Recovery and Rehabilitation<br /><br>Roundtable. </p><br>