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临床试验/NCT05482750
NCT05482750已完成不适用

Effects of Resistance Training Performed in the Fasted State Compared to the Fed State on Morphological and Neuromuscular Adaptations in Young Adults

Federal University of Rio Grande do Sul2 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2022年5月23日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
28
试验地点
2
主要终点
Lean body mass

研究概览

简要总结

It is well evidenced in the literature that fasting aerobic exercise generates a series of metabolic differences when compared to exercise performed in the fed state, including the use of fats predominantly as an energy source. Consequently, increases in adaptations to aerobic training, related to health and physical performance, are observed when sessions are performed in the fasted state. In relation to resistance training, the evidence is limited. There is a lack of data in the literature regarding the effects of fasting on resistance exercises and whether this practice may reflect in losses or improvements in morphological and neuromuscular adaptations related to resistance training. Thus, the aim of the present project is to compare the effects of resistance training performed in the fasted state compared to the fed state during 12 weeks on body composition and physical performance in young adults. Thirty-four eutrophic or overweight individuals, not engaged in regular resistance exercises, aged between 20 and 40 years, will be recruited. They will be put on a standard customized diet and will perform 2 weekly sessions of resistance exercise after overnight fasting (10 to 12 hours) or in the fed state, for 12 weeks. Before, in the middle and after this period, evaluations of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be analyzed. Comparisons will be performed using Generalized Estimating Equations (GEE), adopting the factors group (2 stratifications) and time (3 stratifications). All results will be expressed as mean and standard deviation and the accepted significance level will be 5%.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Triple (Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
19 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Men and women;
  • Aged between 19 and 40 years;
  • Body mass index (BMI) between 18 and 29.9 kg/m²;
  • Not engaged in regular strength physical exercise (>1 weekly session) for the last 3 months.

排除标准

  • Use of medications and/or supplements that may influence the outcomes evaluated;
  • Individuals who have a chronic disease that may prevent physical exercise.

结局指标

主要结局

Lean body mass

时间窗: 15 minutes

Lean body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).

Muscle quality

时间窗: 30 minutes

Muscle quality will be evaluated through echo intensity of the quadriceps through ultrasound (Nemio XG, Toshiba, Japan).

Body mass

时间窗: 1 minute

Body mass will be measured using a scale (Urano, Canoas, Brazil).

Maximum dynamic strength

时间窗: 30 minutes

Maximum dynamic strength will be assessed using the 1 repetition maximum (1RM) test for bench press and knee extension exercises.

Maximum power

时间窗: 30 minutes

The maximum power and the medium power will be evaluated in the bench press and knee extension exercises considering a load of 30 and 70% of 1RM.

Fat body mass

时间窗: 15 minutes

Fat body mass will be determined using the dual energy X-ray absorption (DEXA) method, using a densitometry machine (Hologic GE, Bedford, USA).

Muscle thickness

时间窗: 30 minutes

Muscle thickness will be evaluated through ultrasound (Nemio XG, Toshiba, Japan).

次要结局

未报告次要终点

研究者

发起方
Federal University of Rio Grande do Sul
申办方类型
Other
责任方
Principal Investigator
主要研究者

Eduardo Lusa Cadore

Principal Investigator

Federal University of Rio Grande do Sul

研究点 (2)

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