Analgesic Effectiveness of Three Different Doses of a New Formulation of Lamaline in a Model of Painful Knee (Gonarthrosis)
- Conditions
- Knee Osteoarthritis
- Registration Number
- NCT00264225
- Lead Sponsor
- Solvay Pharmaceuticals
- Brief Summary
This study aims to assess the analgesic effectiveness and safety of three different doses of a new formulation of Lamaline® versus Dafalgan® Codeine after 10 days administration in subjects with painful gonarthrosis
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
- History of knee (unilateral or bilateral) osteoarthritis for at least 6 months
- Pain intensity assessed by Visual Analogue Scale ≥ 40 mm
- Partial functional disability assessed by Lequesne index ≥4 and < than 12
- Patient unable to interrupt his/her NSAIDs to participate in the clinical study
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (171)
Site 3
🇫🇷Andernos Les Bains, France
Site 105
🇫🇷Angers, France
Site 101
🇫🇷Angers, France
Site 103
🇫🇷Angers, France
Site 107
🇫🇷Angers, France
Site 24
🇫🇷L'union, France
Site 106
🇫🇷Angers, France
Site 19
🇫🇷Evreux, France
Site 306
🇫🇷La Garde, France
Site 66
🇫🇷Perpignan, France
Site 2
🇫🇷Albi, France
Site 108
🇫🇷Angers, France
Site 102
🇫🇷Fenioux, France
Site 48
🇫🇷Chatenay Malabry, France
Site 13
🇫🇷Clermont Ferrand, France
Site 319
🇫🇷La Seyne Sur Mer, France
Site 321
🇫🇷La Seyne Sur Mer, France
Site 454
🇫🇷Laval, France
Site 460
🇫🇷Laval, France
Site 118
🇫🇷Les Ponts de Ce, France
Site 458
🇫🇷Laval, France
Site 461
🇫🇷Laval, France
Site 224
🇫🇷Le Pradet, France
Site 23
🇫🇷Limoges, France
Site 49
🇫🇷Lyon, France
Site 22
🇫🇷Libourne, France
Site 70
🇫🇷Millau, France
Site 68
🇫🇷Montpellier, France
Site 30
🇫🇷Montrouge, France
Site 133
🇫🇷Montrevault, France
Site 71
🇫🇷Nice, France
Site 29
🇫🇷Merignac, France
Site 314
🇫🇷Six-fours, France
Site 112
🇫🇷Trelaze, France
Site 410
🇫🇷Tours, France
Site 488
🇫🇷Verzy, France
Site 125
🇫🇷Vihiers, France
Site 46
🇫🇷Evreux, France
Site 20
🇫🇷Fontenay Malabry, France
Site 423
🇫🇷La Rochelle, France
Site 318
🇫🇷La Seyne Sur Mer, France
Site 53
🇫🇷Lyon, France
Site 26
🇫🇷Marseille, France
Site 28
🇫🇷Marseille, France
Site 77
🇫🇷Marseille, France
Site 56
🇫🇷Montpellier, France
Site 62
🇫🇷Montpellier, France
Site 65
🇫🇷Montpellier, France
Site 67
🇫🇷Nimes, France
Site 59
🇫🇷Lyon, France
Site 320
🇫🇷La Seyne Sur Mer, France
Site 225
🇫🇷Le Pradet, France
Site 21
🇫🇷Levallois Perret, France
Site 139
🇫🇷Montreuil Bellay, France
Site 61
🇫🇷Nice, France
Site 57
🇫🇷Nice, France
Site 32
🇫🇷Paris, France
Site 64
🇫🇷Lyon, France
Site 117
🇫🇷Angers, France
Site 432
🇫🇷Chateau-Gontier, France
Site 52
🇫🇷Rennes, France
Site 79
🇫🇷Strasbourg, France
Site 109
🇫🇷Angers, France
Site 110
🇫🇷Angers, France
Site 124
🇫🇷Angers, France
Site 129
🇫🇷Angers, France
Site 121
🇫🇷Angers, France
Site 123
🇫🇷Angers, France
Site 134
🇫🇷Angers, France
Site 138
🇫🇷Angers, France
Site 140
🇫🇷Angers, France
Site 453
🇫🇷Angers, France
Site 498
🇫🇷Angers, France
Site 496
🇫🇷Angers, France
Site 215
🇫🇷Anzin, France
Site 131
🇫🇷Bagneux, France
Site 4
🇫🇷Bassens, France
Site 315
🇫🇷Bandol, France
Site 449
🇫🇷Beaupreau, France
Site 451
🇫🇷Avrille, France
Site 115
🇫🇷Beaucouze, France
Site 502
🇫🇷Beaumont Sur Leze, France
Site 119
🇫🇷Becon Les Granits, France
Site 135
🇫🇷Becon Les Granits, France
Site 136
🇫🇷Becon Les Granits, France
Site 506
🇫🇷Berat, France
Site 50
🇫🇷Beziers, France
Site 213
🇫🇷Bersee, France
Site 5
🇫🇷Bobigny, France
Site 6
🇫🇷Bordeaux, France
Site 122
🇫🇷Briollay, France
Site 55
🇫🇷Beziers, France
Site 7
🇫🇷Brive La Gaillarde, France
Site 8
🇫🇷Carpentras, France
Site 76
🇫🇷Chalons En Champagne, France
Site 9
🇫🇷Chalons En Champagne, France
Site 433
🇫🇷Chateau-Gontier, France
Site 462
🇫🇷Cherbourg, France
Site 10
🇫🇷Clamart, France
Site 11
🇫🇷Clermont Ferrand, France
Site 114
🇫🇷Chemille, France
Site 14
🇫🇷Colmar, France
Site 12
🇫🇷Clermont Ferrand, France
Site 78
🇫🇷Colmar, France
Site 219
🇫🇷Croix, France
Site 47
🇫🇷Dinard, France
Site 507
🇫🇷Eaunes, France
Site 16
🇫🇷Dinan, France
Site 120
🇫🇷Ecouflant, France
Site 15
🇫🇷Dijon, France
Site 17
🇫🇷Dinard, France
Site 18
🇫🇷Evreux, France
Site 207
🇫🇷La Riche, France
Site 25
🇫🇷Marseille, France
Site 209
🇫🇷La Riche, France
Site 459
🇫🇷Laval, France
Site 58
🇫🇷Lyon, France
Site 137
🇫🇷Les Ponts de Ce, France
Site 60
🇫🇷Montpellier, France
Site 27
🇫🇷Marseille, France
Site 51
🇫🇷Nice, France
Site 69
🇫🇷Nimes, France
Site 54
🇫🇷Nice, France
Site 74
🇫🇷Nice, France
Site 73
🇫🇷Nimes, France
Site 63
🇫🇷Nimes, France
Site 130
🇫🇷Noyant, France
Site 128
🇫🇷Parcay Les Pins, France
Site 31
🇫🇷Paris, France
Site 34
🇫🇷Rennes, France
Site 33
🇫🇷Pont de L'arche, France
Site 35
🇫🇷Roquebrune Cap Martin, France
Site 202
🇫🇷Saint Avertin, France
Site 75
🇫🇷Rodez, France
Site 36
🇫🇷Rosny Sous Bois, France
Site 414
🇫🇷Seysses, France
Site 208
🇫🇷Saint Avertin, France
Site 313
🇫🇷Saint-mandrier, France
Site 413
🇫🇷Seysses, France
Site 113
🇫🇷Segre, France
Site 494
🇫🇷Seysses, France
Site 495
🇫🇷Seysses, France
Site 37
🇫🇷Six Fours Les Plages, France
Site 457
🇫🇷St Berthevin, France
Site 38
🇫🇷Six Fours Les Plages, France
Site 489
🇫🇷St Brice Courcelles, France
Site 39
🇫🇷Strasbourg, France
Site 40
🇫🇷Strasbourg, France
Site 132
🇫🇷Thouars, France
Site 126
🇫🇷Tierce, France
Site 104
🇫🇷Tierce, France
Site 221
🇫🇷Toulon, France
Site 228
🇫🇷Toulon, France
Site 301
🇫🇷Toulon, France
Site 302
🇫🇷Toulon, France
Site 44
🇫🇷Toulouse, France
Site 316
🇫🇷Toulon, France
Site 43
🇫🇷Toulouse, France
Site 41
🇫🇷Toulouse, France
Site 511
🇫🇷Toulouse, France
Site 503
🇫🇷Toulouse, France
Site 42
🇫🇷Toulouse, France
Site 45
🇫🇷Toulouse, France
Site 204
🇫🇷Tours, France
Site 201
🇫🇷Tours, France
Site 401
🇫🇷Tours, France
Site 402
🇫🇷Tours, France
Site 405
🇫🇷Tours, France
Site 116
🇫🇷Trelaze, France
Site 72
🇫🇷Vernet Les Bains, France
Site 127
🇫🇷Villebernier, France