Effects of Inspiratory Muscle Training on Postural Stability, Mobility, Activities of Daily Living, Quality of Life and Respiratory Function in Patients With Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Respiratory Function- Forced Expiratory Volume in 1 second
研究概览
简要总结
In this study investigators will examine the effects of inspiratory muscle training and balance training in patients with Parkinson's Disease
详细描述
Parkinson's Disease (PD) is the most common type of Parkinsonism and mainly due to degeneration of basal ganglions and substantia nigra occurs. Balance disorders are one of the common problems in patients with Parkinson's disease. These balance disorders; loss of postural reflexes, insufficiency in postural adjustments, rigidity in the trunk and extremities, and many disorders such as akinesia. Because of balance disorders in patients with PD, increase in addiction to daily life activities, causes physical disability. In the case of PD pulmonary problems may be the leading cause of mortality and mortality. Respiratory symptoms in these patients cause problems in weakness, swallowing, coughing, voice and speech functions. When the investigators look at the current literature, the effect of balance and respiration on Parkinson's patients is found to be seperately but their effect on each other is not sufficiently emphasized. For this reason, the researchers' aim to investigate balance and postural control in patients with Parkinson's disease and to increase the strength of respiratory muscles and to improve balance and postural control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with Parkinson'S Disease
- •Ages between 60 and 85 years
- •Grades 1 to 3 according to Modified Hoehn-Yahr Scale
排除标准
- •Lung surgery or diagnosed lung disease history
- •Having a orthopedic disorder which may affect balance and/or mobility
- •Severe dyskinesia and cognition problems
结局指标
主要结局
Respiratory Function- Forced Expiratory Volume in 1 second
时间窗: Change from baselines to final evaluation at 8th weeks
Forced expiratory volume (FEV) measures how much air a person can exhale during a forced breath. Forced expiratory volume and forced vital capacity are lung function tests that are measured during spirometry. Forced expiratory volume is the most important measurement of lung function. It is used to: Diagnose obstructive lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). A person who has asthma or COPD has a lower FEV1 result than a healthy person. See how well medicines used to improve breathing are working. Check if lung disease is getting worse. Decreases in the FEV1 value may mean the lung disease is getting worse.
Postural Control and Balance
时间窗: Change from baselines to final evaluation at 8th weeks
Biodex Balance System evaluations
Parkinson's Status- Unified Parkinson's Disease Rating Scale
时间窗: Change from baselines to final evaluation at 8th weeks
The UPDRS scale refers to Unified Parkinson Disease Rating Scale, and it is a rating tool used to gauge the course of Parkinson's disease in patients. The UPDRS scale includes series of ratings for typical Parkinson's symptoms that cover all of the movement hindrances of Parkinson's disease. The UPDRS scale consists of the following five segments: 1) Mentation, Behavior, and Mood, 2) ADL, 3) Motor sections, 4) Modified Hoehn and Yahr Scale, and 5) Schwab and England ADL scale. Each answer to the scale is evaluated by a medical professional that specializes in Parkinson's disease during patient interviews.
Inspiratory Muscle Strength
时间窗: Change from baselines to final evaluation at 8th weeks
Maximal inspiratory pressure (MIP) is the most widely used measure of respiratory muscle strength in patients with suspected respiratory muscle weakness. It is determined by measuring upper airway pressure (mouth for outpatients and trachea for intubated or tracheostomized patients) during a maximal voluntary inspiratory effort. The measured pressure is a composite of the pressure generated by the inspiratory muscles and the elastic recoil pressure of the lungs and chest wall.
Respiratory Function- Forced Vital Capasity (FVC)
时间窗: Change from baselines to final evaluation at 8th weeks
Forced vital capacity (FVC) is the total amount of air exhaled during the FEV test. FVC can also help doctors assess the progression of lung disease and evaluate the effectiveness of treatment.
Respiratory Function- Peak Expiratory Flow
时间窗: Change from baselines to final evaluation at 8th weeks
The peak expiratory flow (PEF), also called peak expiratory flow rate (PEFR), is a person's maximum speed of expiration, as measured with a peak flow meter, a small, hand-held device used to monitor a person's ability to breathe out air.
次要结局
- Quality of Life Parameter-Nottingham Health Profile(Change from baselines to final evaluation at 8th weeks)
- Activities of Daily Living-Barthel(Change from baselines to final evaluation at 8th weeks)
- Mobility Status- Rivermead mobility index(Change from baselines to final evaluation at 8th weeks)