概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Uveitis
- 发起方
- Hospices Civils de Lyon
- 入组人数
- 750
- 试验地点
- 1
- 主要终点
- Clinical evolution (persistence or resolution) evaluated by gradation of SEN
- 状态
- 招募中
- 最后更新
- 2年前
概览
简要总结
Uveitis or inflammation of the uveal tract results from a heterogeneous collection of disorders of varying etiologies and pathogenic mechanisms. Uveitis is relatively frequent in industrial countries with an estimation of 115 cases for 100 000 persons and is associated with a blindness risk of 10%. Causes of uveitis can be related to different etiologies (infectious, inflammatory or general inflammatory diseases). Therapeutic care is based on ophthalmologic and systemic diagnosis and treatment strategy depends on the severity of inflammation.
The main objective of the Lyon uveitis study is to analyze the uveitis ophthalmologic etiology and diagnostic and therapeutic care of the patients. This study is proposed to all patients diagnosed for uveitis and referred to the Department of Internal Medicine of the Croix Rousse hospital, Lyon, france for etiologic diagnosis or treatment.
Analysis of i) patients' characteristics, ii) the relevance of complementary exams to determine the uveitis etiology, iii) treatment used.
This study will allow a better characterization of the disease on diagnosis practices and therapeutic care.
研究者
入排标准
入选标准
- •Diagnosis of uveitis
- •First consultation in the Department of Internal Medicine at the Croix-Rousse hospital, Lyon, France
排除标准
- 未提供
结局指标
主要结局
Clinical evolution (persistence or resolution) evaluated by gradation of SEN
时间窗: At one year after diagnosis
Persistence of disease is characterized by persistence of intraocular inflammation evaluated by gradation of SEN. (reference: A Standardization Grading System for Scleritis . Ophthalmology 2011 Apr;118(4):768-71). SEN score ranges from 0 to 5 (resolution = score 0 and persistence = score \>0)