Comparative evaluation of open flap debridement with intramarrow penetration with and without PRF and Bone graft in the treatment of horizontal bone defect- A clinico radiographical study
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 18
- 试验地点
- 1
- 主要终点
- To evaluate the efficacy of clinical and radiographical parameters in open flap debridement and intramarrow penetration alone and with platelet rich fibrin and bone graft.
研究概览
简要总结
This study is designed to be a clinical radiographico study where 18 patients of both the gender with Stage II periodontitis satisfying all the inclusion criteria will be enrolled for the studyThe total sample size calculated is 18 patients. This will be a clinico radiographic study where three sites will be taken. The preoperative protocol comprises of a full mouth scaling and root planing (SRP) treatment, succeeded by meticulous advice regarding oral hygiene protocols. At the 4-week mark, the patients will be recalled for evaluation of persisting pockets followed by flap surgery treatment. Single blinded examiner will perform the clinical examination at baseline, 3 months, and 6 months. After the evaluation of plaque index (PI), gingival index(GI),scores, Periodontal probing depth (PPD),clinical attachment level (CAL) and CBCT radiographical examination, The selected quadrants will be further randomized into Group A, B, and C.
The assessment will be carried out on three groups namely: Group A- open flap debridement with intramarrow penetration alone
Group B- open flap debridement and intramarrow penetration with PRF
**Group C-**open flap debridement and intramarrow penetration with PRF and bone graft
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects who are diagnosed with stage II chronic periodontitis with horizontal defects.Patients with periodontal pocket depths ranging from 5 to 6 mm.
排除标准
- •Systemically compromised patients.
- •Use of antibiotics in the past 6 months Steroid or inflammatory drugs for 7 days in 3 months Known allergy to the above mentioned drugs/substance Smokers and alcoholic Pregnant and lactating women Periodontal therapy within 6 months.
结局指标
主要结局
To evaluate the efficacy of clinical and radiographical parameters in open flap debridement and intramarrow penetration alone and with platelet rich fibrin and bone graft.
时间窗: all clinical parameters and radiographic analysis should be done at baseline, 3 months and 6 months
次要结局
- To compare the results of clinical and radiographical parameters in open flap debridement and intramarrow penetration alone and with platelet rich fibrin and bone graft.(all clinical parameters and radiographic analysis should be done at baseline, 3 months and 6 months and compare their results)
研究者
Dr Suchitra B
coorg institute of dental sciences