Testing the Efficacy and Safety of Niacinamide Cosmetic Preparation: A Randomised, Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- skin oiliness assessment with sebumeter probe
研究概览
简要总结
Niacinamide in lower concentrations has been recognized as a cosmetic ingredient with hydrating properties. Therefore, aim was to test the efficacy and safety of niacinamide cosmetic preparation in A Randomized, Controlled Trial.
详细描述
Skin hydration (as use of hydrating cosmetic ingredients) is one of the most interventions for healthy skin and skin barrier function. Therefore, cosmetic ingredients used for this purpose should be examined for their efficacy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy volunteers who gave written informed consent
排除标准
- •skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation
结局指标
主要结局
skin oiliness assessment with sebumeter probe
时间窗: through study completion, an average of 1 year
sebum level
Hydration assessment with corneometer probe
时间窗: through study completion, an average of 1 year
stratum corneum hydration
TEWL assessment with Courage Khazaka probe
时间窗: through study completion, an average of 1 year
Transepidermal water loss
pigmentation assessment with mexameter probe
时间窗: through study completion, an average of 1 year
erythema and melanin
次要结局
- subjective opinion of participants(through study completion, an average of 1 year)
研究者
Dario Leskur
assistant professor
University of Split, School of Medicine