Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Not Applicable

Completed

• Conditions: Sensitive Skin
• Interventions: Device: Quantitative Sensory Testing

• Registration Number: NCT03081403
• Lead Sponsor: University Hospital, Brest

Brief Summary

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin.

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Detailed Description

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress...

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Study Timeline

• Study First Submitted: 2017-03-10
• Study First Submitted QC: 2017-03-10
• Study First Posted: 2017-03-16
• Study Start: 2017-04-14
• Primary Completion: 2017-09-22
• Study Completion: 2017-10-27
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-03
• Last Update Posted: 2025-02-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• Age: between 20 and 60 years
• Cooperating patient
• Informed and written consent of the subject
• Affiliated to the social security
• For subjects with sensitive skin:

subjects with a score greater than 50 on the scale sensitive scale

• To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion Criteria

• Adults subject with legal protection
• Subject in a social institution.
• Subject with major cognitive or psychiatric disorders
• Subject with pathological use of alcohol or consumption of another drug.
• Subject with skin involvement of the back of the dominant hand or malformation.
• Known sensitive neuropathy
• Pregnant woman
• Subject receiving medical treatment which may interfere with the results.
• Subject with treatment in the back of the dominant hand.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Subjects without sensitive skin	Quantitative Sensory Testing	Subjects with result lower than 20 on the sensitive scale
Subjects with sensitive skin	Quantitative Sensory Testing	Subjects with a score greater than 50 on the sensitive scale

Primary Outcome Measures

Name	Time	Method
Cutaneous perception threshold	6 months	The cutaneous perception threshold of pain to heat.

Secondary Outcome Measures

Name	Time	Method
The cutaneous perception threshold of vibration	6 months	The cutaneous perception threshold of pain to harm.
The cutaneous perception threshold of cold	6 months	The cutaneous perception threshold of cold

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France