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Clinical Study to Compare Efficacy and Safety of AVT06 and EU-Eylea (ALVOEYE)

Phase 3
Recruiting
Conditions
neovascular (wet) AMD
Registration Number
JPRN-jRCT2031220316
Lead Sponsor
Koelbl Stephanie
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
62
Inclusion Criteria

Subject must be >= 50 years of age, at the time of signing the informed consent.
- Subjects must be diagnosed with neovascular (wet) AMD in the study eye.
- Subjects must have active, treatment naive, subfoveal CNV lesions secondary to neovascular (wet) AMD.
- Willingness and ability to undertake all scheduled visits and assessments.

Exclusion Criteria

- Any prior systemic treatment with anti-VEGF therapy
- Any condition that, in the Investigator's opinion, can interfere with full participation in the study, including administration of the study treatment and attending required visits; can pose a significant risk to the participant, or interfere with interpretation of study data
- Prior treatment with any investigational drugs within 30 days or 5 half-lives (whichever is longer) of the previous investigational treatment before initiation of the study treatment or concomitant enrollment in any other clinical study involving an investigational study treatment
- Subjects not suitable for participation, whatever the reason, as judged by the Investigator, including medical or psychiatric conditions, or participants potentially at risk of noncompliance to study procedures.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change from baseline to Week 8 in BCVA as measured by ETDRS letter score.
Secondary Outcome Measures
NameTimeMethod
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