Effect of Patient Position on Arterial, End-tidal and Transcutaneous Carbon Dioxide Partial Pressure in Patients Undergoing Laparoscopic Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 142
- 主要终点
- Difference between arterial and end-tidal carbon dioxide pressures
研究概览
简要总结
Investigators evaluate the effect of patient position (Trendelenburg and reverse Trendelenburg) on arterial, end-tidal and transcutaneous carbon dioxide partial pressure in patients undergoing laparoscopic surgery.
详细描述
Investigators evaluate the effect of patient position (Trendelenburg and reverse Trendelenburg) on arterial, end-tidal and transcutaneous carbon dioxide partial pressure in patients undergoing laparoscopic surgery. Arterial carbon dioxide partial pressure is assessed intermittently before, during, and after pneumoperitoneum. End-tidal and transcutaneous carbon dioxide partial pressure are continuously monitored.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients undergoing laparoscopic surgery (expected duration of pneumoperitoneum > 1 hour) in the Trendelenburg or reverse Trendelenburg positions
排除标准
- •hemodynamically unstable patients due to decompensated heart failure, sepsis, or symptomatic arrhythmia, etc.
- •symptomatic pulmonary disease, chronic obstructive pulmonary disease
研究组 & 干预措施
Trendelenburg group
Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the Trendelenberg position
干预措施: Arterial carbon dioxide monitoring (Other)
Trendelenburg group
Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the Trendelenberg position
干预措施: End-tidal carbon dioxide monitoring (Other)
Trendelenburg group
Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the Trendelenberg position
干预措施: Transcutaneous carbon dioxide monitoring (Other)
reverse Trendelenburg group
Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the reverse Trendelenberg position
干预措施: Arterial carbon dioxide monitoring (Other)
reverse Trendelenburg group
Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the reverse Trendelenberg position
干预措施: End-tidal carbon dioxide monitoring (Other)
reverse Trendelenburg group
Arterial, end-tidal, and transcutaneous carbon dioxide partial pressure are monitored in the reverse Trendelenberg position
干预措施: Transcutaneous carbon dioxide monitoring (Other)
结局指标
主要结局
Difference between arterial and end-tidal carbon dioxide pressures
时间窗: baseline before CO2 pneumoperitoneum, every 30 minute during CO2 pneumoperitoneum, and 15 min after deflation of CO2
Difference between arterial and end-tidal carbon dioxide partial pressures are calculated. (Arterial carbon dioxide partial pressure minus end-tidal carbon dioxide partial pressure)
次要结局
- Agreement among arterial, end-tidal, and transcutaneous carbon dioxide partial pressure(baseline before CO2 pneumoperitoneum, every 30 minute during CO2 pneumoperitoneum, and 15 min after deflation of CO2)
研究者
Jin-Young Hwang
Associate professor
SMG-SNU Boramae Medical Center