ACTRN12611000082909撤回4 期
A double blind randomised controlled trial assessing the effect of zoledronate on marrow fat in older osteoporotic persons after suffering a minimal trauma fracture
SWAHS - Clinical Governance Office0 个研究点目标入组 60 人开始时间: 2011年1月21日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 65 Years 至 100 Years（—）
- 性别
- Female
入选标准
- •1- History of minimal trauma fracture within 90 days before starting the trial
- •2- Age: Older than 65
排除标准
- •1) Patients taking statins for cholesterol lowering
- •2) Previous history of diabetes mellitus
- •3)creatinine clearance < 35 ml/min
- •4)pre-existing hypocalcemia must be treated by adequate intake of calcium and vitamin D before therapy with zoledronic acid
- •5)active history of uveitis, iritis, or episcleritis
- •6)metastatic cancer or cancer diagnosed less than 2 years ago where treatment is still ongoing
- •7)Active primary hyperparathyroidism
- •8)Hypothyroidism, not appropriately controlled with long-term thyroxine therapy
- •9)Serum 25-hydroxyvitamin D concentrations <15 ng/
研究者
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