Functional connectivity changes in multisensory cortical areas in patients with spatial neglect treated with subliminal galvanic vestibular stimulatio

Phase 4

Recruiting

Conditions: I63.9
R29.5
Cerebral infarction, unspecified

Registration Number: DRKS00024442

Lead Sponsor: Klinik und Poliklinik für NeurologieKlinikum der Universität München, Campus Großhadern

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 120

Inclusion Criteria

1st ever ischemic or hemorrhagic stroke (lacunar infarcts are tolerable)
Age > 18. LJ
Capacity to consent
Ability to complete study investigations

Neglect Group:
Neglect group (one or more of the following findings):
Gaze preference to the side of the lesion.
Impaired visuospatial and motor - exploration in the contralesional space.
Inability to respond to stimuli in the contralesional space
At least 2 abnormal neglect tests

Exclusion Criteria

Multiple strokes / history of stroke (except small lacunes)
brainstem / cerebellar infarcts
extensive vascular leukencephalopathy (Fazekas >II)
respiratory / cardiac insufficiency
edema (displacement of midline structures, compression of CSF spaces)
neurodegenerative disease (MoCA<20)
Acute psychiatric disease with limited insight
Active tumor with life expectancy <1 year
skin irritation around the mastoid
Epilepsy (except symptomatic early seizures)
previous disorder of the vestibular system with permanent dysfunction of the vestibular endorgans
Cardiac pacemaker
Brain pacemaker
non-MRI-capable metal parts after surgery
cardiac stents < 3 months
shrapnel
large tattoos

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
compensation of spatial neglect using paper / pencil neglect tests, Catherine Bergego scale, test battery for attention testing (TAP) after three weeks of treatment with subliminal GVS

Secondary Outcome Measures