Measuring the Electrical Properties of Malignant Tissues In Vivo

• Conditions: Neoplasms

• Registration Number: NCT02747225
• Lead Sponsor: Southern Medical University, China

Brief Summary

Previously published studies have indicated that there exist difference in electrical properties (EPs), i.e., the conductivity and relative permittivity, between malignant and adjacent normal tissue, which will be useful in the early detection of cancers. However the EP information mainly based on ex vivo measurement of cancer tissues, and few data in vivo were published. The purpose of this study is to in vivo measure the electrical properties of the malignant tissues.

Detailed Description

The measurements were safety guaranteed and were conducted during the cancer surgeries. Before the tissue was excised from the patient,the pathologist assisted the operator (already at the operating room) responsible for the measurement.The measurement of malignant and corresponding normal tissues were both performed. The tissues for dielectric properties measurement were classified as normal or malignant by the pathologist based on his own expertise and decision criteria (visual inspection, anatomy) and the per-operative histological examination. The measurements were directly performed on the tissue before excision.The sites of the measured malignant tissues were marked,doubletracked according to the pathological report to make sure the marked sites are malignant. The patient age and tissue temperature at the time of measurement were recorded.

Study Timeline

• Study First Submitted: 2016-02-22
• Study First Submitted QC: 2016-04-18
• Study First Posted: 2016-04-21
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-11
• Last Update Posted: 2018-10-12
• Study Start: 2018-12
• Primary Completion: 2019-06
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Clinical diagnosis of cancer Disease

Exclusion Criteria

• None

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Conductivity of the Malignant Tissues measured In Vivo	one year
Relative Permittivity of the Malignant Tissues measured In Vivo	one year

Trial Locations

Locations (1)

Southern medical university; 🇨🇳 Guangzhou, Guangdong, China