A study to compare various scoring systems to predict the severity of acute pancreatitis (sudden inflammation of pancreas) caused by gallstones.

Completed

• Conditions: Biliary acute pancreatitis,

• Registration Number: CTRI/2021/01/030634
• Lead Sponsor: Indira Gandhi Medical College

Brief Summary

Acute pancreatitis, which is sudden inflammation of the pancreas, is a common disease requiring hospitalisation. There are various causes of acute pancreatitis, out of which gallstones are the most common cause. Severe acute pancreatitis is not very common (20%) however associated with very high complication and mortality rate compared to mild pancreatitis. If we can predict as to which patients will develop severe pancreatitis, it will help a lot in the management of these patients. Many scoring systems and markers are available for this purpose. In this proposed study various scoring systems (Ranson, Glasgow, BISAP, JSS and MCTSI) will be compared for the prediction of severe acute pancreatitis. All patients of acute gallstone induced pancreatitis presenting to the department of surgery will be included in this study and the above mentioned scores will be calculated for each one of them. These patients will then be observed daily from the day of admission to the day of discharge/death and the severity of acute pancreatitis will be ascertained as per the revised Atlanta classification. This data will be compared to the scoring systems included in this study and the best scoring system to predict severe acute gallstone induced pancreatitis will be determined. This will help a lot in the management of patients with acute gallstone induced pancreatitis in the future.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-22
• Study Completion: 2021-07-31
• Last Update Posted: 2022-08-03

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

All patients of acute gallstone induced pancreatitis presenting to the emergency department of IGMC Shimla.

Exclusion Criteria

• Pregnant females 2.
• Patients below 18 years of age.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prediction of severe acute gallstone induced pancreatitis by various scoring systems.	Baseline, 5 days, 10 days and 15 days

Secondary Outcome Measures

Name	Time	Method
Mortality rate in patients of acute gallstone induced pancreatitis.	Baseline, 5 days, 10 days and 15 days

Trial Locations

Locations (1)

Indira Gandhi Medical College; 🇮🇳 Shimla, HIMACHAL PRADESH, India

Indira Gandhi Medical College

🇮🇳Shimla, HIMACHAL PRADESH, India

Mukul Sharma

Principal investigator

7018547474

mukulmuki@gmail.com