Influence of antimicrobial photodynamic therapy compared to local application of minocycline microspheres on the healing results after non-surgical periodontal therapy: a controlled randomized clinical trial over 12 months

Not Applicable

• Conditions: K05.3; K05.1; Chronic periodontitis; Chronic gingivitis

• Registration Number: DRKS00010732
• Lead Sponsor: Poliklinik für Zahnerhaltung und Parodontologie Universitätsklinikum Regensburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-03-19
• Study Start: 2016-06-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

age =35 years
- minimum of 16 residual teeth
- untreated generalized moderate to severe chronic periodontitis with characteristic clinical inflammation symptoms
- minimum of 4 teeth with probing pocket depth =6mm
- approximal plaque index (API) =25%
- papillary bleeding index (PBI) =25%

Exclusion Criteria

- heavy smokers (=10 cigarettes/day in the last 12 months)
- uncontrolled medical conditions
- use of systemic antibiotics during the last three months
- periodontal treatment during the last three months
- pregnant or lactating females
- aggressive periodontitis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
clinical healing results after 6 weeks, 3 months, 6 months and 12 months following non-surgical periondontal therapy (? probing pocket depth, ? clinical attachment level, ? bleeding on probing)

Secondary Outcome Measures

Name	Time	Method
microbiological healing results after 6 weeks, 3 months, 6 months and 12 months following non-surgical periodontal therapy (reduction of microbiological load with periodontal pathogens)