Randomized phase II study comparing chemotherapy led by using the classification of primary tumor origin with empirical chemotherapy for patients with unknown primary cancer .
- Conditions
- cancer of unknown primary
- Registration Number
- JPRN-UMIN000001919
- Lead Sponsor
- Ministry of Health, Labour and Welfare scientific research Nakagawa squad
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 120
Not provided
(1)cases with the adaptation of radical operation and the radical irradiation (2)Patient subgroups known to have favorable features are excluded. These subgroups include as follows: (a)women with adenocarcinoma involving only axillary lymph nodes (b)women with adenocarcinoma involving the peritoneal cavity (c)patients with squamous cell carcinoma involving only cervical lymph nodes (d)patients with squamous cell carcinoma involving only inguinal lymph nodes (e)patients with poorly differentiated carcinoma consistent with a germ cell tumor or neuroendcrine carcinomas (f)men with osteosclerosis-related bone metastases and elevated PSA in their plasma or tumor (3)active infection or other severe complications (such as gastrointestinal bleeding, heart disease) (4)symptomatic brain tumor (5)interstitial pneumonitis or pulmonary fibrosis (6)patients who underwent bone marrow transplantation (7)patients who underwent peripheral blood stem cell transplantation (8)severe drug allergy (9)alcohol intolerance (10) HBsAg(+) (11)pregnant or lactating women (12)men with the pregnant intention (13)uncontrollable diabetis mellitus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method