ongitudinal Imaging of Lumbar Patients and Controls

Not Applicable

• Conditions: Acute Lumbar Pain; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12614000147684
• Lead Sponsor: Macquarie University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-02-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

For case participants:
1. Present to a primary care practitioner with recent onset low back pain of less than 2 weeks duration
2. To be available to enrol in study and have initial MRI scan within 3 weeks from onset of pain episode
3. Current pain intensity greater than or equal to 5 on numerical pain rating scale (0-10 scale)
4. The current episode of low back pain started suddenly (pain intensity increased by at least 5 points on NPRS over a period of less than 24 hours)
5. Age less than 50 years of age
For control participants:
1. No current low back pain
2. A maximum of two previous low back episodes.

Exclusion Criteria

1. Nerve root compromise, previous spinal surgery, canal stenosis, fracture, cancer, inflammatory joint diseases, infection, or cauda equina” syndrome
2. Inadequate English language or cognitive abilities to complete outcome measures
3. Contraindication to MRI.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in MRI findings[12 weeks];Change in pain (NPRS)[12 weeks]

Secondary Outcome Measures

Name	Time	Method
Cross-sectional comparison of physical examination findings and MRI findings at baseline.[Day 1 - physical assessment and baseline MRI performed sequentially on the same day.]