Comparison of the effects of two herbal mouthwashes and chlorhexidine mouthwash on the growth of a particular bacteria in patients with dental braces.

Phase 4

Not yet recruiting

• Conditions: patients requiring fixed orthodontic treatment

• Registration Number: CTRI/2019/11/021905
• Lead Sponsor: Sujitha

Brief Summary

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|Curcumin mouthwash is reported to be effective against harmful microorganisms as in chlorhexidine mouthwash. However, its effect against streptococcus mutans colony which is implicated to cause dental caries in humans and reported to be increased in patients undergoing orthodontic treatment has not been reported yet. Similarly, Rosemary has been tested and found to be effective against microbial biofilms. However, their effect in conjunction with curcumin has not been reported. Thus, by testing the effectiveness of curcumin mouthwash, curcumin-rosemary mouthwash and chlorhexidine mouthwash it could be established that curcumin mouthwash or curcumin- rosemary mouthwash could be used as a safe and economical alternative to chlorhexidine mouthwash.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-04-11
• Study Start: 2019-11-15

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 48

Inclusion Criteria

• patients who has come for orthodontic treatment.
• patients with permanent dentition.

Exclusion Criteria

• patients with active carious lesions and periodontal disease.
• patients with mouth breathing and thumb sucking habit.
• patients with smoking habit 4.
• patients on antibiotic therapy or probiotics.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
there is no significant difference in the effects of the three mouthwashes against the growth of S.mutans bacteria in orthodontic patients	pre-treatment, 1 month after bonding orthodontic bracket, 1 month after the use of mouthwash

Secondary Outcome Measures

Name	Time	Method
There is a significant difference in the effects of the three mouthwashes against the growth of S.mutans bacteria in orthodontic patients	pre-treatment, 1 month after bonding orthodontic bracket, 1 month after the use of mouthwash

Trial Locations

Locations (1)

SRM dental college; 🇮🇳 Thiruvallur, TAMIL NADU, India

SRM dental college

🇮🇳Thiruvallur, TAMIL NADU, India

sujitha S

Principal investigator

8939746154

sujithasridharan@gmail.com