To evaluate effect of Guduchyadi Kwath Yoni Prakshalan (Vaginal Douching) in the treatment of vaginitis

Phase 2/3

Not yet recruiting

Conditions: Subacute and chronic vaginitis. Ayurveda Condition: YONIROGAH/YONI-VYAPADAH,

Registration Number: CTRI/2022/08/045097

Lead Sponsor: University Post Graduate Institute of Ayurved Studies and Research Jodhpur Rajasthan

Brief Summary: Vaginitis is a common complaint in women, accounting for 7% of all visits to gynecologist and being the most common gynecologic problem encountered by primary care providers for women.Vaginitis is the inflammation of the vagina characterized by abnormal vaginal discharge, itching, burning and pain.Noninfectious causes including atrophic, irritant, allergic, and inflammatory vaginitis are less common and account for 5% to 10% of vaginitis cases.The acidic environment of vagina created by naturally occurring bacteria in the normal vaginal flora prevents infection.The most common causes of vaginitis are bacterial vaginosis, vulvovaginal candidiasis and trichomoniasis. Bacterial vaginosis is implicated in 40% to 50% of cases when a cause is identified with vulvovaginal candidiasis accounting for 20% to 25% and trichomoniasis for 15% to 20% of cases.Vaginitis is a common medical problem in women that is associated with substantial discomfort and frequent medical visits. Roughly 5 to 10 million office visits per year are attributed to vaginitis.

*Guduchyadi KwathaYoni Prakshalana* will be selected for this study given in *Charak Chikitsa Yonivyapad Guduchyadi Kwatha (Guduchi, Triphala, Danti)*,the drug *Guduchi* has *Tikta Kashaya Rasa, Guru Snigdha Guna,Ushna Veerya,Madhura Vipaka* and having properties like *Tridoshaara, Balya, Stambhana, Kandughna, Yonisodhana, Vedanasthapana, Shothahara, Dahaprashamana, Vranashodana,* and *Vranaropana.* The drug *Danti* has *Katu Rasa, Guru, Tikshnaguna, Ushnavirya, Katuvipaka, Kaphavatahara*, property. The drugs in *Triphala* has *Tridoshahara, Rasayanam, Bhedana, Anulomana* property*. Stambhana*property of *Guduchyadi Kwathayoni Prakshalana* helps to reduce *Yonisrava* (Vaginal discharge). Due to *Ushnaveerya* of drugs pacifies *Vata Dosha* and relive *Yoni Toda* (vaginal pain). Due to *Krimi* or *Jantughnaproperty* of drugs, relive *Yonikandu.*

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 30

Inclusion Criteria

1.Married women 2.Patients suffering from any of the two following sign and symptoms Vaginal pain,Vaginal discharge,Vulval itching / vaginal irritation,Burning micturition 3.Painful intercourse due to vaginitis.

Exclusion Criteria

1.Pregnant women 2.Unmarried women 3.Patient have positive HbsAg , HIV , VDRL 4.Hypersensitivity to drug and inability to confine to protocol.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in the Vaginal Itching, Burning Micturition, Vaginal discharge,Inflammation, Tenderness	60 Days

Secondary Outcome Measures

Name	Time	Method
Improvement in Dyspareunia, Fever.	60 days

Trial Locations

Locations (1): University Post Graduate Institute of Ayurved Studies and Research
🇮🇳
Jodhpur, RAJASTHAN, India
University Post Graduate Institute of Ayurved Studies and Research
🇮🇳Jodhpur, RAJASTHAN, India
Dr Santosh Vishnoi
Principal investigator
8952052073
santoshbishnoi0025@gmail.com