Efficacy of Antimicrobial Coating Suture Coated Vicryl Plus Compared With Vicryl in Reduced Surgical Site Infection of Dental Implant Surgeries: A Uni-Blind Randomized Clinical Trial Study

Not Applicable

Completed

• Conditions: Infection, Surgical Site
• Interventions: Drug: Vicryl plus

• Registration Number: NCT03659344
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Patients randomly aligned in 2 groups.Vicryl plus sutures were used in group 1 for closing subperiostal flaps after dental implant surgeries and vicryl sutures were used in group 2.

Detailed Description

Patients were divided randomly based on computer randomization list in two groups: In group1, vicryl plus 4-0 (Vicryl Plus Ethicon,Johnson \& Johnson Company, Sommerville, NJ) suture was used to close surgical site and Vicryl 4-0 (Vicryl Ethicon,Johnson \& Johnson Company, Sommerville, NJ) in group II.

All dental implants were placed through creating subperiosteal flaps. In each group, fresh socket placed dental implants were documented. Patients were visited in 1, 2, 3 and 4 weeks after dental implant surgeries.

Postoperative infection was defined as local erythematous change in the sutured wound with purulent discharge or localized abscess formation on surgical site. If wound dehiscence occurred, it was documented.

Patients were blind about what suture was used.

Study Timeline

• Study Start: 2016-09-01
• Primary Completion: 2018-02-01
• Study Completion: 2018-07-30
• Study First Submitted: 2018-08-31
• Status Verified: 2018-09
• Study First Submitted QC: 2018-09-03
• Last Update Submitted: 2018-09-03
• Study First Posted: 2018-09-06
• Last Update Posted: 2018-09-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 320

Inclusion Criteria

• Need 3 dental implants at the posterior of the mandible

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Exclusion Criteria

• Diabetic patients
• smoker
• poor oral hygiene

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Vicryl plus	Vicryl plus	In this group, vicryl plus(Triclosan coated) sutures were used to close flaps

Primary Outcome Measures

Name	Time	Method
The prevalence of post-operative infection	In one month	The number of participants who had local erythematous change in the sutured wound with purulent discharge or localized abscess formation on surgical site.
The prevalence of post-operative dehiscence	In one month	The number of participants who had relatively or completely open wound