跳至主要内容
临床试验/NCT07051837
NCT07051837已完成不适用

Background: Isometric Handgrip (IHG) is a Classic Sympatho- Excitatory Stimulus Often Used in Autonomic Testing. Aims: The Aims of This Study Were to Evaluate the Acute Cardiovascular Response and Recovery Following Isometric Handgrip (HG) Exercise-induced Fatigue on Healthy Adults. Secondary, to Examine Correlations Between Isometric Handgrip Strength and Both Systolic (SBP) and Diastolic (DPB) Blood Pressure' Methods: Study Was a Repeated Measure Single Group Design. Thirty-five Healthy Volunteers, 20 Females and 15 Males, Age (36.16 + 6.11years) Were Enrolled in the Study. Study Was at Out

October 6 University1 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2024年4月2日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
35
试验地点
1
主要终点
to evaluate the acute cardiovascular response and recovery following isometric handgrip exercise-induced fatigue on healthy adults. and to examine correlations between isometric handgrip strength and both systolic and diastolic blood pressure

研究概览

简要总结

: Isometric handgrip (IHG) is a classic sympatho- excitatory stimulus often used in autonomic testing.

Aims: The aims of this study were to evaluate the acute cardiovascular response and recovery following isometric handgrip (HG) exercise-induced fatigue on healthy adults. Secondary, to examine correlations between isometric handgrip strength and both systolic (SBP) and diastolic (DPB) blood pressure' Methods: Study was a repeated measure single group design. Thirty-five healthy volunteers, 20 females and 15 males, age (36.16 + 6.11years) were enrolled in the study. Study was at out Clinic of October 6 University. Demographic data were collected at beginning of session. Subjects were then assessed for baseline (BL) blood pressure (BP). Maximal isometric voluntary contraction (MIVC) for each subject was the average of two-5 seconds MIVCs of dominant hand using a hand-held dynamometer separated by 1 minute of rest. Subjects were allowed 5 minutes rest, then performed fatigue protocol (FP) using the hand-held dynamometer with their dominant hand at 50% MIVC for 3 minutes as a One minute of rest was given following FP then subjects were reassessed for BP and MIVC of dominant hand respectively (Immediate reassessment). Further, BP was reassessed for 3 times at 5 minutes interval between measures.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
20 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Participants should fulfil the criteria set for age and BMI ranges. All participants should be medically stable and normotensive. They should not have any physical limitations that prevent performance of IHG exercises.

排除标准

  • Patients will be excluded from the study if they are smokers, under any medications, diabetics, diagnosed with cardiovascular diseases. Also if they have orthopaedic limitations or mental problems that affect the participation and the result of the study

结局指标

主要结局

to evaluate the acute cardiovascular response and recovery following isometric handgrip exercise-induced fatigue on healthy adults. and to examine correlations between isometric handgrip strength and both systolic and diastolic blood pressure

时间窗: from April 2024toMay 2025

Maximal isometric voluntary contraction (MIVC) for each subject was the average of two-5 seconds MIVCs of dominant hand using a hand-held dynamometer separated by 1 minute of rest. Subjects were allowed 5 minutes rest, then performed fatigue protocol (FP) using the hand-held dynamometer with their dominant hand at 50% MIVC for 3 minutes as a One minute of rest was given following FP then subjects were reassessed for BP and MIVC of dominant hand respectively (Immediate reassessment). Further, BP was reassessed for 3 times at 5 minutes interval between measures

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amira Mohamed Afify

ASSOCIATE PROFESSOR OF 1Department of Physical Therapy for Cardiopulmonary Disorders and Geriatrics, Faculty of Physical Therapy

October 6 University

研究点 (1)

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