Does Acetaminophen Reduce Neuraxial Analgesic Requirement During Labor
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Neuraxial Analgesic Drug Consumption Per Hour
研究概览
简要总结
The hypothesis is if administration of acetaminophen during labor will reduce the amount of neuraxial pain medication required for comfort. For the study, Acetaminophen or placebo capsules will be administered at the time of neuraxial analgesia placement and then administered every 6 hours until delivery. Overall consumption of neuraxial pain medication will be determined.
详细描述
Acetaminophen 1000 mg or placebo capsules will be administered at the time of neuraxial analgesia placement and continued every 6 hours until delivery. Vital signs, scores for pain, nausea, itching, and sleepiness will be also obtained. Evaluation of consumption of neuraxial analgesic medication will be included in the final analysis for the differences between the 2 groups
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •>/= 18 years of age not allergic to study medications
排除标准
- •pre-eclampsia in labor AND with demonstrated significant abnormal liver enzyme function changes non-English speaking subjects
研究组 & 干预措施
acetaminophen
1000 mg every 6 hours during labor up to maximum 3 doses
干预措施: Acetaminophen (Drug)
placebo
placebo capsule identical to the acetaminophen capsule will be administered every 6 hours to a maximum of 4 doses
干预措施: Placebo (Drug)
结局指标
主要结局
Neuraxial Analgesic Drug Consumption Per Hour
时间窗: up to 24 hours
subject evaluated every 2 hours with the amount of neuraxial analgesia consumed during that time period. Study med administered up to 24 hours. labor analgesia continue until delivery.
次要结局
未报告次要终点