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临床试验/CTRI/2024/06/069615
CTRI/2024/06/069615尚未招募不适用

An Open Labelled Clinical Study To Evaluate The Efficacy Of Virechana Karma Followed By Baladi Yapna Basti With Prishtha Dhara In The Management Of Kati-Prishtha-Trika Graha With Special Reference To Ankylosing Spondylitis

National Institute Of Ayurveda1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年7月22日最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
尚未招募
入组人数
30
试验地点
1
主要终点
Changes In Lumbar Spine Motion

研究概览

简要总结

Ankylosing spondylitis is a type of arthritis that causes inflammation in the joints and ligaments of the spine. It may also affect peripheral joints like the knees, ankles, and hips. Normally, the joints and ligaments in the spine help us move and bend. If you have ankylosing spondylitis, the inflammation in the joints and tissues of the spine can cause stiffness. In severe cases, this may cause the vertebrae (bones in the spine) to fuse (grow together). When the vertebrae fuse, it can lead to a rigid and inflexible spine. The most common symptom of ankylosing spondylitis is lower back and/or hip pain and stiffness. Over time, the symptoms may progress to other areas of the spine or body. The pain typically worsens during periods of rest or inactivity, which may cause some people to experience more pain during the middle of the night or after prolonged sitting. Usually, moving and exercise can help improve pain. On the basis of pathogenesis and Symptoms can be correlated to clinical conditions Pravruddha Amavata (TrikSaruja Shotha),Asthimajjagata Vata (Asthi, parva bheda,Sandhishoola, Aswapna, Satat ruk, Vinaamta), Kaphavrit Vyana (Guruta Sarvagatranam, Kati Sarva Sandhyasthi Ruja, Gatisanga) mentioned in classical texts.

But due to the maximum proximity of symptoms and pathology,  AS in present study is being correlated to Kati-Prishtha-TrikaGraha. Shoola (Pain), and Graha (Stiffness) in Kati(Pelvis), Prishtha (Posterior region of trunk from neck to pelvis), and Trik Pradesha (Region around shoulder girdle) are the cardinal features of Ankylosing Spondylitis. In Ayurveda, Graha (Stiffness) is one of the characteristic features of aggravated Vata associated with Ama Dosha.

AIM:

To evaluate the efficacy of Virechana karma followed Baladi YapnaBasti, Bhutikadi Taila Anuvasna Basti and Prishtha Dhara in the management of Kati-Prishtha-Trika graha (Ankylosing Spondylitis)

OBJECTIVE:

To evaluate the efficacy of Virechana Karma followed by Baladi Yapna Basti, Bhutikadi Taila Anuvasna Basti and Prishtha Dhara in the management of Kati-Prishtha-Trika Graha with special reference to Ankylosing spondylitis

RESEARCH QUESTION:

Is there any efficacy of Virechana Karma followed by Baladi Yapna Basti , Bhutikadi Taila Anuvasna Basti and Prishtha Dhara in tha management of Kati Prishtha-Trik Graha (Ankylosing Spondylitis)?

HYPOTHESIS:

Null Hypothesis [H0]: There is no efficacy of Virechana Karma followed by Baladi Yapna Basti,  Bhutikadi Taila Anuvasna Basti and Prishtha Dharain the management of Kati-Prishtha-Trik Graha(Ankylosing Spondylitis)

Alternative Hypothesis [HA]: There is significanct efficacy of Virechana karma followed by Baladi Yapna basti , Bhutikadi Taila Anuvasna Basti and Prishtha Dhara in the management of Kati-Prishtha Trik Graha (Ankylosing Spondylitis)

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patient having symptoms of Kati-Prishtha-Trika Graha.
  • Patient having sign and symptoms of Ankylosing spondylitis.
  • Chronicity: Less than 10 years.
  • Patients indicated for Virechana,Basti Karma and Prishtha Dhara.
  • Age 18-60 years.

排除标准

  • Patients having serious Cardiac, Renal or Hepatic diseases, uncontrolled Hypertension, Diabetes.
  • Pregnant & lactating women.
  • Patients contraindicated for Virechana, Basti Karma and Prishtha Dhara.

结局指标

主要结局

Changes In Lumbar Spine Motion

时间窗: 15th day from completion of procedure

次要结局

  • Changes in :(1.Pain)

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Sneh Kanwar Rathore

National Institute of Ayurveda

研究点 (1)

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