Suprainguinal Fascia Iliaca Compartment Block Versus Anterior Quadratus Lumborum Block for Analgesia After Total Hip Arthroplasty: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Total opioids use for 24 hours
研究概览
简要总结
Patients undergoing total hip arthroplasty are randomly assigned to two groups (fascia iliaca compartement block [FICB] group or quadratus lumborum block [QLB] group). In the FICB group, ultrasound-guided suprainguinal FICB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is performed on the ipsilateral surgical side at the end of surgery. In the QLB group, ultrasound-guided anterior QLB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery. A standardized multimodal analgesic regimen is used for postoperative pain control. The total use of opioids including patient-controlled analgesia and rescue analgesics is compared in both groups for 24 hours after surgery. The amount of opioids used is compared by conversion to oral morphine equivalent dose. Pain score at rest and movement during postoperative 24 hours, time to first request for analgesics, the incidence of side effects, patient satisfaction for pain control at postoperative 24 hours, quality of recovery at postoperative 24 hours, time to discharge readiness, and hospital length of stay are compared.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients between the ages of 19 and 70 undergoing total hip arthroplasty under spinal anesthesia
- •Be able to provide written consent to participate in clinical trials, understand the procedures of this clinical trial, and be able to properly fill out patient-reported questionnaires
- •ASA physical status classification 1-2
排除标准
- •ASA physical status classification 3-4
- •Patients who are contraindicated to nerve blocks (hypersensitivity to local anesthetics, infection at the injection site, etc.)
- •Patients with chronic pain and taking pain medications, antidepressants, and anticonvulsants
- •Other major medical or psychiatric conditions that will affect response to treatment
- •Refusal of intravenous patient-controlled analgesia
- •Patients determined to be unsuitable for this clinical trial by the researchers
结局指标
主要结局
Total opioids use for 24 hours
时间窗: Over the first 24 hours after surgery
Total dose of opioids used upto 24 hours after surgery (morphine milligram equivalents)
次要结局
- Time to first request for pain medication(From the end of surgery to discharge, an average of 4 days)
- Postoperative pain with movement (Numeric rating scale)(At postoperative 4, 8, 12, 16, 20, 24 hours)
- Hospital length of stay(From the end of surgery to discharge, an average of 4 days)
- Postoperative pain at rest (Numeric rating scale)(At postoperative 4, 8, 12, 16, 20, 24 hours)
- Incidence of postoperative nausea and vomiting(Over the first 24 hours after surgery)
- Patient satisfaction score with pain control at 24 hours after surgery(At 24 hours after surgery)
- Quality of Recovery at 24 hours after surgery(At 24 hours after surgery)
- Time to discharge readiness(From the end of surgery to discharge, an average of 4 days)
研究者
Seokha Yoo
Clinical Assistant Professor
Seoul National University Hospital