Fascia Iliaca Compartment Block Versus Quadratus Lumborum Block in Total Hip Arthroplasty

Not Applicable

Completed

• Conditions: Nerve Block; Pain, Postoperative
• Interventions: Procedure: fascia iliaca compartement block; Procedure: quadratus lumborum block

• Registration Number: NCT05228028
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Patients undergoing total hip arthroplasty are randomly assigned to two groups (fascia iliaca compartement block \[FICB\] group or quadratus lumborum block \[QLB\] group). In the FICB group, ultrasound-guided suprainguinal FICB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is performed on the ipsilateral surgical side at the end of surgery. In the QLB group, ultrasound-guided anterior QLB (30 ml of 0.375% ropivacaine with 75 µg of epinephrine) is done on the ipsilateral surgical side at the end of surgery. A standardized multimodal analgesic regimen is used for postoperative pain control. The total use of opioids including patient-controlled analgesia and rescue analgesics is compared in both groups for 24 hours after surgery. The amount of opioids used is compared by conversion to oral morphine equivalent dose. Pain score at rest and movement during postoperative 24 hours, time to first request for analgesics, the incidence of side effects, patient satisfaction for pain control at postoperative 24 hours, quality of recovery at postoperative 24 hours, time to discharge readiness, and hospital length of stay are compared.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-01-18
• Study First Submitted QC: 2022-02-07
• Study First Posted: 2022-02-08
• Study Start: 2022-03-22
• Primary Completion: 2022-10-21
• Status Verified: 2022-12
• Study Completion: 2022-12-22
• Last Update Submitted: 2022-12-26
• Last Update Posted: 2022-12-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Adult patients between the ages of 19 and 70 undergoing total hip arthroplasty under spinal anesthesia
• Be able to provide written consent to participate in clinical trials, understand the procedures of this clinical trial, and be able to properly fill out patient-reported questionnaires
• ASA physical status classification 1-2

Exclusion Criteria

• ASA physical status classification 3-4
• Patients who are contraindicated to nerve blocks (hypersensitivity to local anesthetics, infection at the injection site, etc.)
• Patients with chronic pain and taking pain medications, antidepressants, and anticonvulsants
• Other major medical or psychiatric conditions that will affect response to treatment
• Refusal of intravenous patient-controlled analgesia
• Patients determined to be unsuitable for this clinical trial by the researchers

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
fascia iliaca compartement block [FICB] group	fascia iliaca compartement block	-
quadratus lumborum block [QLB] group	quadratus lumborum block	-

Primary Outcome Measures

Name	Time	Method
Total opioids use for 24 hours	Over the first 24 hours after surgery	Total dose of opioids used upto 24 hours after surgery (morphine milligram equivalents)

Secondary Outcome Measures

Name	Time	Method
Time to first request for pain medication	From the end of surgery to discharge, an average of 4 days	Time to first request for pain medication after surgery
Postoperative pain with movement (Numeric rating scale)	At postoperative 4, 8, 12, 16, 20, 24 hours	Postoperative pain with movement (Numeric rating scale; minimum 0, maximum 10, a higher score means more pain)
Hospital length of stay	From the end of surgery to discharge, an average of 4 days	Days of hospitalization after surgery until discharge
Postoperative pain at rest (Numeric rating scale)	At postoperative 4, 8, 12, 16, 20, 24 hours	Postoperative pain at rest (Numeric rating scale; minimum 0, maximum 10, a higher score means more pain)
Incidence of postoperative nausea and vomiting	Over the first 24 hours after surgery	Incidence of postoperative nausea and vomiting (%)
Patient satisfaction score with pain control at 24 hours after surgery	At 24 hours after surgery	Patient satisfaction score with pain control at 24 hours after surgery (minimum 0, maximum 10, a higher score means higher satisfaction)
Quality of Recovery at 24 hours after surgery	At 24 hours after surgery	Quality of Recovery at 24 hours after surgery assessed by QoR-15 questionnaire
Time to discharge readiness	From the end of surgery to discharge, an average of 4 days	Days of hospitalization after surgery until discharge readiness (defined as satisfying the following three criteria; (1) adequate pain control (numeric rating scale score \< 4), (2) no intravenous opioid use in the past 12 hours, and (3) able to walk at least 30 m without time limit)

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of