IRCT20200328046886N5招募中2 期
Evaluation of Effect of N-acetylcysteine On Rate and Severity of Colistin Nephrotoxicity: A Randomized Double-blind Placebo-controlled Trial
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 48
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Patients over 18 years old
- •Use of colistin for five days or longer as IV antimicrobial therapy in patients with nosocomial infections
- •Obtaining a written informed consent form from all patients or their guardians
排除标准
- •Receive NAC less than 24 hours before the first dose of colistin
- •Patients undergoing hemodialysis or peritoneal dialysis
- •Receiving contrast material for radiological imaging
- •Pregnant and lactating women
- •Known allergy to colistin or N-acetylcysteine (NAC)
- •Patient with recent history of cardiopulmonary resuscitation
- •Patients with systolic blood pressure <90 mmHg
- •GFR<60 ml/min
研究者
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