Transversalis Fascia Plane Block and Rectus Sheath Block in Renal Transplantation Donors

Not Applicable

• Conditions: Postoperative Pain
• Interventions: Procedure: Transversalis fascia plane block and rectus sheath block; Device: Intravenous fentanyl patient control device

• Registration Number: NCT05324215
• Lead Sponsor: Koc University Hospital

Brief Summary

Transversalis fascia plane block (TFPB) is a relatively new, easy-to-apply and safe regional anesthesia technique used to provide postoperative analgesia in various surgeries. It has been shown that TFPB and rectus sheath block (RSB) administration reduces opioid consumption and related side effects in patients undergoing surgery with general anesthesia. To our knowledge, there is no study examining TFPB in donor nephrectomy.

The investigators aimed to prospectively examine the effect of TFPB and RSB on opioid consumption in postoperative period on donors who will undergo laparoscopic nephrectomy in renal transplantation surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-02-17
• Status Verified: 2022-04
• Study First Submitted: 2022-04-05
• Study First Submitted QC: 2022-04-05
• Last Update Submitted: 2022-04-11
• Study First Posted: 2022-04-12
• Last Update Posted: 2022-04-18
• Primary Completion: 2023-02-17
• Study Completion: 2023-02-17

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Donor patients scheduled for elective nephrectomy in renal transplantation surgery
• American Society of Anesthesiologists (ASA) I-II
• Patients who are aged between 18-75

Exclusion Criteria

• Skin infection at the block area
• Coagulation disorder and using anticoagulant drugs
• End-stage organ and system failure
• Severe pulmonary and/or cardiovascular problems
• Substance addiction or known psychiatric or mental problems
• Chronic painkiller usage

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Transversalis Fascia Plane Block and Rectus Sheath Block Group	Transversalis fascia plane block and rectus sheath block	Transversalis Fascia Plane Block and Rectus Sheath Block will be administered to this group.
Transversalis Fascia Plane Block and Rectus Sheath Block Group	Intravenous fentanyl patient control device	Transversalis Fascia Plane Block and Rectus Sheath Block will be administered to this group.
Control Group	Intravenous fentanyl patient control device	No regional anesthesia technique will be applied to the control group.

Primary Outcome Measures

Name	Time	Method
Total opioid consumption retrieved from patient records	up to 24 hours	the amount of fentanyl required by the patient and given by the device will be recorded for the first 24 hours.

Secondary Outcome Measures

Name	Time	Method
Numeric Rating Scale (NRS)	up to 24 hours	Pain of patients will be evaluated and recorded according to NRS. A NRS requires the patient to rate their pain on a defined scale between 0 and10 (0 is no pain and 10 is the worst pain)

Trial Locations

Locations (1)

Koç University Hospital; 🇹🇷 Istanbul, Zeytinburnu, Turkey