Effect of probiotic in patients with Multiple Sclerosis
- Conditions
- Multiple Sclerosis.Multiple sclerosis
- Registration Number
- IRCT20181210041918N2
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Selection based on revised Mc Donald criteria
a relapsing–remitting course
one or more documented relapses in the previous year or two or more in the previous 2 years
a score of 0 to 5.5 on the EDSS
Age range between 18 to 55
Unwillingness to continue cooperation
Exacerbation of the disease during the study
There is a relapse during the intervention
History of antibiotic use during 1 month ago
Consumption of any probiotic and prebiotic supplement and antibiotic in the last 1 month
Consumption supplements containing of vitamin, fiber, omega-3, anti-oxidants during 3 weeks before and during the study.
Taking non-steroidal anti-inflammatory drugs (NSAIDs), estrogen, progesterone, immunosuppressions, diuretics and corticosteroids drugs.
History of gastroenteritis during the last month
History of intestinal surgery during the past month
Inflammatory bowel disease (IBD), rheumatoid arthritis, systemic lupus, type 1 diabetes and other autoimmune diseases and pregnancy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method