Randomized controlled trial to apply personalized medicine to treatment-resistant depression with mixed feature.
Not Applicable
Recruiting
- Conditions
- Treatment-resistant depression with or without mixed feature.
- Registration Number
- JPRN-UMIN000020735
- Lead Sponsor
- Kansai Medical University, Osaka, Japan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Not provided
Exclusion Criteria
Patients who meet DSM5 for significant Axis I and II disorders except major depressive disorder. Patients who have a ECT therapy within 3 months prior to study entree. Patients who are comatose and strongly affected by central nervous system. Patients known to have a history or complication of allergy to aripiprazole. Patients with a history or a complication of diabetes. Women who are pregnant, possibly pregnant, or breast-feeding. Patients who have been judged by the investigator to be inappropriate for inclusion in the trial for any other reasons Patients who have been judged by the investigators to have a high risk of suicide.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Remission rate and percent change of Hamilton rating scale for depression 17 (HAM-D17)
- Secondary Outcome Measures
Name Time Method Cognitive function test, NEO-FFI, Home Environment Questionarie