Randomized Controlled Trial Investigating Cold Snare aNd Forcep polypectomY Among Small POLYPs in Rates of Complete Resection: the TINYPOLYP Trial.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Colo-rectal Cancer
- Sponsor
- Stanford University
- Enrollment
- 181
- Locations
- 1
- Primary Endpoint
- Completeness of resection
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
The focus of the study is to evaluate impact of cold forcep and cold snare in achieving complete resection during polypectomy of polyps <=3mm during colonoscopy.
Detailed Description
The details of the proposed study are as follows: 1. Experimental group: using cold forceps for polyps \<=3mm of the colon 2. Control group: using cold snare for polyps \<=3mm of the colon 3. Methods: 1. Colonoscopy will be performed in the same standard of care manner as if no study was taking place. 2. If polyps \<=3mm are identified, the endoscopist is randomized to performing polypectomy with cold forcep or cold snare. 3. After removal of the polypectomy, two biopsies are performed at the margin of the polypectomy site to identify residual lesion. 4. The polyp as well as well as the two biopsies are reviewed by a pathologist.
Investigators
Shai Friedland
Professor in Gastroenterology & Hepatology
Stanford University
Eligibility Criteria
Inclusion Criteria
- •Patients 18 years or older
- •Polyps \<=3mm
Exclusion Criteria
- •Inflammatory bowel disease
- •Polyposis syndromes
Outcomes
Primary Outcomes
Completeness of resection
Time Frame: 2 weeks
The primary outcome measured is comparison of completeness of resection between the cold forcep and cold snare groups.
Secondary Outcomes
- Time to resection(During the procedure)
- Complications(4 weeks)
- Number of forcep bites or snare attempts(During the procedure)