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2 Doses of an Approved Drug Being Studied for a New Indication for the Prevention of Postoperative Nausea and Vomiting (0869-091)

Phase 3
Completed
Conditions
Postoperative Nausea and Vomiting
Registration Number
NCT00090246
Lead Sponsor
Merck Sharp & Dohme LLC
Brief Summary

The purpose of this study is to assess the safety and efficacy of 2 doses of an approved drug for a new indication in the prevention of postoperative nausea and vomiting in patients receiving general anesthesia for open abdominal surgery requiring overnight hospital stay.

Detailed Description

The duration of treatment is 4 weeks.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
922
Inclusion Criteria
  • Patient is at least 18 years of age.
  • Patient is scheduled to undergo open abdominal surgery requiring overnight hospital stay (24-hour hospital stay after end of surgery).
  • Patient is scheduled to receive general anesthesia.
  • Patient is scheduled to receive postoperative opioids.
Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Prevention of PONV in the 24 hours following end of surgery; Tolerability24 hours
Secondary Outcome Measures
NameTimeMethod
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