Stellate ganglion block in patients with borderline personality disorder and posttraumatic stress disorder

Not Applicable

• Conditions: F60.31; F43.1; Post-traumatic stress disorder

• Registration Number: DRKS00015817
• Lead Sponsor: Klinik für Anästhesiologie und Operative Intensivmedizin, Schmerzzentrum,Universitätsmedizin Mannheim

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-10-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Diagnosis of a borderline personality disorder (5 criteria DSM) + perhaps posttraumatic stress disorder
Age of 18 to 50 years
voluntary consent

Exclusion Criteria

chronic pain
Bipolar-I-disorder or schizophrenia
Cognitive impairment
Allergies on local anesthetics
Intake of oral anticoagulants

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction of dissociative symptoms and inner tension in patients with routine treatment (Dialectical Behavioral Therapy, Bohus et al. 2004) combined with ultrasound guided SGB (Stellate Ganglion Blocks) in contrast to patients without the intervention (SGB).<br>The effectivness is measured with standardized questionars: every meeting Dissociations-Tension-Scale-4 (DSS-4) and the Clinical Global Impression Skala (CGI). Once per week the Beck-Depression-Inventar (BDI), Borderline-Symptom-List-23 (BSL-23), State-Trait-Anxiety-inventory-S (STAI-S), PTSD Checklist for DSM-5 (PCL-5). Before and after the intervention series the patient has to fill up the Questionnaire of dissociative symptoms (FDS) and the Symptom-Checklist-90-R (SCL-90-R).<br>

Secondary Outcome Measures

Name	Time	Method
Further we want to investigate the effectiveness on wound healing after self-injury in upper extremities with a standardized questionaire: Patient and Observer Scare Assessment Scale (POSAS).