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Clinical Study on Lupin�s Ayurvedic Nasal Spray in COVID-19 patients and household contacts

Phase 2
Completed
Conditions
Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Registration Number
CTRI/2021/08/036089
Lead Sponsor
upin Ltd
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
138
Inclusion Criteria

1. Capable of understanding and providing signed informed consent and ability to adhere to the requirements and restrictions of this protocol.

2. Subjects with mild COVID-19 symptoms (only for Treatment Group). Subjects with uncomplicated upper respiratory tract infection (without shortness of breath or hypoxia [normal saturation i.e. SpO2 levels �94%]), may have mild grade of fever ( <1000 C), cough, sore throat, nasal congestion, malaise and headache.

3. Participants staying with COVID-19 subject in the same household (only for Prevention Group).

4. Participants who have tested positive for RT-PCR (for treatment group only) and negative for RT-PCR (for prevention group only) within 5 days of enrollment

Exclusion Criteria

1. Subjects with moderate to severe disease

2. Subjects requiring or likely requiring oxygen support in the opinion of investigator

3. Any clinical contraindications, as judged by the investigator

4. Pregnant or lactating females

5. Subjects with prior history of confirmed COVID-19 infection with RT-PCR in last 3 months.

6. Subjects who are currently hospitalized or need for hospitalization

7. Subjects with blocked nose requiring intranasal decongestant

8. Any history of underlying uncontrolled medical illness (such as diabetes, hypertension, liver disease or history of alcoholism, HIV or any other serious medical illness)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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