Personalized Pork: Dose-dependent Identification of Unique Biomarkers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Metabolic biomarker discovery
研究概览
简要总结
The purpose of the research is to assess the dose-dependent impacts of the consumption of fresh pork on blood-borne metabolites (markers) following the controlled feeding of pork
详细描述
Eligible participants will follow 3 randomly ordered 4-week feeding periods varying only with the consumption of 0, 3 or 6 oz of pork or a 50:50 blend of chicken and beef (6, 3 and 0 oz for respective trials to ensure similar total poultry/meat intake among trials).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •generally healthy (i.e., an absence of diagnosed chronic illnesses and inborn metabolic disorders)
- •Age 18-65
- •all races
- •both sexes
- •willingness to comply with the research diet requirements
排除标准
- •special dietary needs (e.g., vegetarianism, gluten-free, etc.)
- •use of medication known to influence metabolism
- •substance use
研究组 & 干预措施
0 oz Pork
Participants receive 0 oz pork and 6 oz 50:50 blend of chicken and beef per day
干预措施: Pork Consumption (Dietary Supplement)
3 oz Pork
Participants receive 3 oz pork and 3 oz 50:50 blend of chicken and beef per day
干预措施: Pork Consumption (Dietary Supplement)
6 oz Pork
Participants receive 6 oz pork and 0 oz 50:50 blend of chicken and beef per day
干预措施: Pork Consumption (Dietary Supplement)
结局指标
主要结局
Metabolic biomarker discovery
时间窗: 4 weeks
Biomolecules detected through metabolomic profiling that will result in discovery of a metabolic signature for pork intake
次要结局
- HDL Cholesterol(4 weeks)
- Triglycerides(4 weeks)
- LDL-Cholesterol(4 weeks)
- Interleukin-6(4 weeks)
- Total Cholesterol(4 weeks)
- C-Reactive Protein(4 weeks)
- Fasted Glucose(4 weeks)
- Insulin(4 weeks)
- Blood Pressure(4 weeks)
- Body Composition(4 weeks)
研究者
Shirin Hooshmand
Professor
San Diego State University