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UCSF BP Activate Letter Study

Not Applicable
Completed
Conditions
Hypertension
Interventions
Other: Control Letter
Other: BP Activate Letter
Registration Number
NCT06152094
Lead Sponsor
University of California, San Francisco
Brief Summary

The BP Activate Study aims to assess the effectiveness of the BP Report letter with personalized BP medication recommendations, compared with Control letters and no intervention, at shortening time to appointment, time to visit, time to medication change, and time to achievement of BP goal.

Detailed Description

The BP Activate Study is a randomized quality improvement trial. We will deliver one of two versions of a letter to established English-speaking primary care patients at Mt Zion with uncontrolled hypertension, defined by SBP\>140 or DBP\>90 in the past two years (identified via EHR). The letter will prompt patients to schedule a visit with their provider or team nurse practitioner to discuss their BP recommendations with their clinician. We will test 2 versions of the letter and a usual care control:

1. The "BP Activate Report Letter" group will get a letter that presents recommendations for medication changes from a computerized algorithm using the patient's medical records and recommends discussing these specific recommendations with their clinician; or

2. The "Control Letter" group will get a letter that suggests they talk to their clinician about their BP without providing any specific medication recommendations.

3. The "Usual Care" group will not receive any intervention.

This primary goal of the study is to assess the effectiveness of the BP Activate Report Letter compared with the Control Letter, and see if it shortens time to appointment, time to visit, time to medication change (primary outcome), and time to achievement of BP goal. Clinicians, with patient input, will still have full control of how BP is clinically managed. A small number of patients will be contacted by a research coordinator to hear what they thought when they received the letter, and why they did or did not act upon the information.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
484
Inclusion Criteria
  • Patient is a primary care patient of a clinician in a general internal medicine clinic who has agreed to have their patients participate in the study
  • Lowest SBP>140 or lowest DBP>90 at last visit in general internal medicine clinic
  • Last visit in general internal medicine clinic was < 2 years ago
  • EngageRx algorithm determines that a medication intensification step is indicated
Exclusion Criteria
  • Primary language is not English
  • Patient's provider indicates (through an active opt-out process) that they do not want the patient to receive a BP Activate letter

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Control LetterControl LetterParticipants in the Control Letter arm will receive a Control letter suggesting they talk to their clinician about their blood pressure (without BP history or specific medication recommendations).
BP Activate LetterBP Activate LetterParticipants in the BP Activate Letter arm will receive a BP Report letter that includes computerized algorithm recommendations for medication changes they should discuss with their clinician.
Primary Outcome Measures
NameTimeMethod
Time to medication change or demonstrated BP control at 6 months6 months

Time is measured as number of days between randomization date and the day that a participant is prescribed a new anti-HTN medication or an increase in dose of a prior anti-HTN medication, or they have a documented BP measurement \<140 mmHg systolic and \<90 mmHg diastolic.

Secondary Outcome Measures
NameTimeMethod
Time to BP goal at 3 months3 months

Time is defined as number of days from randomization until first documentation of a BP measurement \<140 mmHg systolic and \<90 mmHg diastolic.

Time to medication change at 6 months6 months

Time is measured as number of days between randomization date and the day that a participant is prescribed a new anti-HTN medication or an increase in dose of a prior anti-HTN medication.

Time to completed visit at 3 months3 months

Time to medication change is defined as number of days between randomization and the day the participant completes a visit in the Division of General Internal Medicine.

Time to medication change at 3 months3 months

Time is measured as number of days between randomization date and the day that a participant is prescribed a new anti-HTN medication or an increase in dose of a prior anti-HTN medication.

Time to completed visit at 6 months6 months

Time to medication change is defined as number of days between randomization and the day the participant completes a visit in the Division of General Internal Medicine.

Time to medication change or demonstrated BP control at 3 months3 months

Time is measured as number of days between randomization date and the day that a participant is prescribed a new anti-HTN medication or an increase in dose of a prior anti-HTN medication, or they have a documented BP measurement \<140 mmHg systolic and \<90 mmHg diastolic.

Time to BP goal at 6 months6 months

Time is defined as number of days from randomization until first documentation of a BP measurement \<140 mmHg systolic and \<90 mmHg diastolic.

Trial Locations

Locations (1)

University of California, San Francisco

🇺🇸

San Francisco, California, United States

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