A Randomised Study Comparing Tissue Conservation in Conventional Versus Mohs' Surgery of Basal Cell Carcinoma

Not Applicable

Completed

• Conditions: Carcinoma, Basal Cell
• Interventions: Procedure: standard surgery; Procedure: Mohs micrographic surgery

• Registration Number: NCT00571363
• Lead Sponsor: NHS Tayside

Brief Summary

We have compared to types of surgery to assess which one leaves the smaller surgical defect.

Detailed Description

Patients with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 centimetre and 1 centimetre away from eyes, nose and ears were either randomized to undergo Mohs Micrographic Surgery or standard surgical excision. After the tumour had been removed the defect was measured.

Study Timeline

• Study Start: 2004-01
• Study Completion: 2006-12
• Status Verified: 2007-12
• Study First Submitted: 2007-12-11
• Study First Submitted QC: 2007-12-11
• Last Update Submitted: 2007-12-11
• Study First Posted: 2007-12-12
• Last Update Posted: 2007-12-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Subjects with a clinical diagnosis of a nodular basal cell carcinoma of less than 1 cm, 1 cm away from eye, nose or ears

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Exclusion Criteria

• Subjects of less than 18 years of age
• Subjects unable to comply with instructions,
• Immunosuppressed subjects

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
standard surgery	standard surgery	basal cell carcinomas were excised with 4 mm margins
Mohs	Mohs micrographic surgery	Basal cell carcinoma were removed via Mohs Micrographic surgery

Primary Outcome Measures

Name	Time	Method
defect size after surgery	immediately after surgery

Trial Locations

Locations (1)

Ninewells Hospital and Medical School; 🇬🇧 Dundee, United Kingdom