NCT00777842终止不适用
Silencing the c-Myc Gene Using Third Generation Antisense Restenosis Therapy
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 19
- 试验地点
- 1
- 主要终点
- Vessel Lumen Patency
研究概览
简要总结
The GTX™ Drug Eluting Coronary Stent System is intended for the treatment of patients with a lesion in the coronary artery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient has discrete de novo lesion of a coronary artery with symptomatic ischemic heart disease
- •Planned treatment of one lesion with a single stent
- •Denovo type A, B1 lesions with a Reference diameter between 3.0 and 3.5mm and a lesion length between 5 and 16mm
排除标准
- •Diabetic (HbA1C >6.0)
- •Platelet count < 100000 cells/mm3 or > 700000 cells/mm3; WBC < 3000 cells/mm3; or a hemoglobin < 10 g/dl
- •Renal dysfunction with creatinine > 2.0 mg/dl
- •Patient has a known pre-dilatation ejection fraction (EF) less than forty five (<45%)
- •Myocardial infarction (MI) less than 3 months prior to intervention
- •Patient has type B2, C lesion
- •Reference artery diameter <3.0 or >3.6 mm
- •Target lesion length < 5mm and >16 mm
- •Other stenosis >50% in target vessel
- •Known hypersensitivity or contraindication to aspirin, clopidogrel, ticlopidine, or cobalt chromium, or a sensitivity to contrast agent that, in the opinion of the investigator, cannot be adequately premedicated.
研究组 & 干预措施
1
Experimental
Device
干预措施: GTX™ Drug Eluting Coronary Stent System (Device)
结局指标
主要结局
Vessel Lumen Patency
时间窗: 6 months
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
进行中（未招募）
2 期
Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMDnAMDWet Age-related Macular DegenerationNeovascular AMDwAMDWet AMDCNVNeovascular Age-related Macular DegenerationAMDChoroidal NeovascularizationNCT04704921AbbVie671
已完成
不适用
Complex All-comers and Patients With Diabetes or Prediabetes, Treated With Xience Sierra Everolimus-eluting StentsAngina PectorisCoronary StenosisCoronary Artery DiseaseAngina, UnstableCoronary RestenosisMyocardial InfarctionAcute Coronary SyndromeNCT04475380Foundation of Cardiovascular Research and Education Enschede1,757
已完成
不适用
Medtronic RevElution TrialCoronary Artery DiseaseNCT02480348Medtronic Vascular109
已完成
不适用
Rapid Acute Coronary Syndrome Exclusion Using High-sensitivity I TroponinChest PainMyocardial IschemiaNCT04488913Henry Ford Health System32,609
已完成
2 期
RGX-314 Gene Therapy Pharmacodynamic Study for Neovascular Age-related Macular Degeneration (nAMD)Wet Macular DegenerationWet Age-related Macular DegenerationNeovascular Age-related Macular DegenerationNCT04832724AbbVie60