The Use of Stroke Mobile Application and Tele-medicine to shorten the time of Thrombolytic treatment at The Spoke Hospital of King Chulalongkorn Memorial Hospital
- Conditions
- Ischemic strokeThrombolysisDoor-to-needle timeFavorable functional outcome
- Registration Number
- TCTR20181103002
- Lead Sponsor
- Chulalongkorn Stroke Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 64
1.Diagnosis of ischemic stroke causing measurable neurological deficit
2.Onset of symptoms <4.5 hours before beginning treatment
3.Aged ≥18 years
1.Significant head trauma or prior stroke in previous 3 months
2.Symptoms suggest subarachnoid hemorrhage
3.Arterial puncture at noncompressible site in previous 7 days
4.History of previous intracranial hemorrhage,Intracranial neoplasm, arteriovenous malformation
5.Elevated blood pressure (systolic >185 mm Hg or diastolic >110 mm Hg)
6.Active internal bleeding
7.Acute bleeding diathesis, including but not limited to
8.Platelet count <100 000/mm³
9.Heparin received within 48 hours, resulting in abnormally elevated aPTT greater than the upper limit of normal
10.Current use of anticoagulant with INR >1.7 or PT >15 seconds
11.Current use of direct thrombin inhibitors or direct factor Xa inhibitors with elevated sensitive laboratory tests (such as aPTT, INR, platelet count, and ECT; TT; or appropriate factor Xa activity assays)
12.Blood glucose concentration <50 mg/dL (2.7 mmol/L)
13.CT demonstrates multilobar infarction (hypodensity >1/3 cerebral hemisphere)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to receive intravenous thrombolysis 60 minutes Door-to-needle time
- Secondary Outcome Measures
Name Time Method Favorable functional outcome 3 months modified Rankin scale