Study on the Patient-Ventilator Asynchrony Analysis Function

Not Applicable

Not yet recruiting

• Conditions: To Study the Incidence of Patient-ventilator Asynchronization in Two Groups of Patients Under Two Conditions With PVA Unsynchronization Analysis Function

• Registration Number: NCT06390917
• Lead Sponsor: Ming Zhong

Brief Summary

In this study, the incidence of patient-ventilator asynchronism in two groups of patients was studied when the ventilator was prompted by the PVA asynchronism analysis function

Detailed Description

Incidence of patient-computer dyssynchrony events: defined as the proportion of patient-computer dyssynchrony events in the total number of cycles during the patient trial. The observation period began 48 hours after the participants met the inclusion and exclusion criteria and signed the informed consent, and the data collection was stopped 48 hours later.

Study Timeline

• Status Verified: 2024-04
• Study First Submitted: 2024-04-18
• Study Start: 2024-04-20
• Study First Submitted QC: 2024-04-29
• Last Update Submitted: 2024-04-29
• Study First Posted: 2024-04-30
• Last Update Posted: 2024-04-30
• Primary Completion: 2024-08-20
• Study Completion: 2024-12-24

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Adults (≥18 years) requiring invasive mechanical ventilation
2. Patiens had spontaneous breathing;
3. Agreed to participate in the trial and signed an informed consent

Exclusion Criteria

1. Patients with contraindications to esophageal catheter insertion and inability to monitor esophageal pressure;
2. pregnant women;
3. patients with severe central nervous system damage or neuromuscular related diseases;
4. Participating in other clinical research projects;
5. Patients deemed unsuitable by the investigator

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Incidence rate of PVAs	48 hours	Percentage of the number of respiratory cycles in which human-machine asynchronous events occurred in the total number of respiratory cycles in each patient during the trial

Secondary Outcome Measures

Name	Time	Method
Accuracy of PVA recognition function	48 hours	Compare manual audit and machine judgment
The proportion of PVAs that were identified by the investigator among the total PVAs during the trial	48 hours
Incidence of PVA within half an hour before and after the intervention	Half an hour before and after the intervention